Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

Nat Metab     Michael Aregger , Keith A Lawson , Maximillian Billmann , Michael Costanzo , Amy H Y Tong , Katherine Chan , Mahfuzur Rahman , Kevin R Brown , Catherine Ross , Matej Usaj , Lucy Nedyalkova , Olga Sizova , Andrea Habsid , Judy Pawling , Zhen-Yuan Lin , Hala Abdouni , Cassandra J Wong , Alexander Weiss , Patricia Mero , James W Dennis , Anne-Claude Gingras , Chad L Myers , Brenda J Andrews , Charles Boone , Jason Moffat

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.

Proteomics     James E Tomkins , Sybille Dihanich , Alexandra Beilina , Raffaele Ferrari , Nicolò Ilacqua , Mark R Cookson , Patrick A Lewis , Claudia Manzoni

Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.

Mol. Psychiatry     N Amin , E Byrne , J Johnson , G Chenevix-Trench , S Walter , I M Nolte , kConFab Investigators , J M Vink , R Rawal , M Mangino , A Teumer , J C Keers , G Verwoert , S Baumeister , R Biffar , A Petersmann , N Dahmen , A Doering , A Isaacs , L Broer , N R Wray , G W Montgomery , D Levy , B M Psaty , V Gudnason , A Chakravarti , P Sulem , D F Gudbjartsson , L A Kiemeney , U Thorsteinsdottir , K Stefansson , F J A van Rooij , Y S Aulchenko , J J Hottenga , F R Rivadeneira , A Hofman , A G Uitterlinden , C J Hammond , S-Y Shin , A Ikram , J C M Witteman , A C J W Janssens , H Snieder , H Tiemeier , B H R Wolfenbuttel , B A Oostra , A C Heath , E Wichmann , T D Spector , H J Grabe , D I Boomsma , N G Martin , C M van Duijn

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state.

Nat. Struct. Mol. Biol.     Feng Li , Frédéric Pincet , Eric Perez , Claudio G Giraudo , David Tareste , James E Rothman

Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.

PLoS Genet.     Marilyn C Cornelis , Keri L Monda , Kai Yu , Nina Paynter , Elizabeth M Azzato , Siiri N Bennett , Sonja I Berndt , Eric Boerwinkle , Stephen Chanock , Nilanjan Chatterjee , David Couper , Gary Curhan , Gerardo Heiss , Frank B Hu , David J Hunter , Kevin Jacobs , Majken K Jensen , Peter Kraft , Maria Teresa Landi , Jennifer A Nettleton , Mark P Purdue , Preetha Rajaraman , Eric B Rimm , Lynda M Rose , Nathaniel Rothman , Debra Silverman , Rachael Stolzenberg-Solomon , Amy Subar , Meredith Yeager , Daniel I Chasman , Rob M van Dam , Neil E Caporaso

Genome-wide association study identifies eight loci associated with blood pressure.

Nat Genet     Christopher Newton-Cheh , Toby Johnson , Vesela Gateva , Martin D Tobin , Murielle Bochud , Lachlan Coin , Samer S Najjar , Jing Hua Zhao , Simon C Heath , Susana Eyheramendy , Konstantinos Papadakis , Benjamin F Voight , Laura J Scott , Feng Zhang , Martin Farrall , Toshiko Tanaka , Chris Wallace , John C Chambers , Kay-Tee Khaw , Peter Nilsson , Pim van der Harst , Silvia Polidoro , Diederick E Grobbee , N Charlotte Onland-Moret , Michiel L Bots , Louise V Wain , Katherine S Elliott , Alexander Teumer , Jian'an Luan , Gavin Lucas , Johanna Kuusisto , Paul R Burton , David Hadley , Wendy L McArdle , Wellcome Trust Case Control Consortium , Morris Brown , Anna Dominiczak , Stephen J Newhouse , Nilesh J Samani , John Webster , Eleftheria Zeggini , Jacques S Beckmann , Sven Bergmann , Noha Lim , Kijoung Song , Peter Vollenweider , Gerard Waeber , Dawn M Waterworth , Xin Yuan , Leif Groop , Marju Orho-Melander , Alessandra Allione , Alessandra Di Gregorio , Simonetta Guarrera , Salvatore Panico , Fulvio Ricceri , Valeria Romanazzi , Carlotta Sacerdote , Paolo Vineis , Inês Barroso , Manjinder S Sandhu , Robert N Luben , Gabriel J Crawford , Pekka Jousilahti , Markus Perola , Michael Boehnke , Lori L Bonnycastle , Francis S Collins , Anne U Jackson , Karen L Mohlke , Heather M Stringham , Timo T Valle , Cristen J Willer , Richard N Bergman , Mario A Morken , Angela Döring , Christian Gieger , Thomas Illig , Thomas Meitinger , Elin Org , Arne Pfeufer , H Erich Wichmann , Sekar Kathiresan , Jaume Marrugat , Christopher J O'Donnell , Stephen M Schwartz , David S Siscovick , Isaac Subirana , Nelson B Freimer , Anna-Liisa Hartikainen , Mark I McCarthy , Paul F O'Reilly , Leena Peltonen , Anneli Pouta , Paul E de Jong , Harold Snieder , Wiek H van Gilst , Robert Clarke , Anuj Goel , Anders Hamsten , John F Peden , Udo Seedorf , Ann-Christine Syvänen , Giovanni Tognoni , Edward G Lakatta , Serena Sanna , Paul Scheet , David Schlessinger , Angelo Scuteri , Marcus Dörr , Florian Ernst , Stephan B Felix , Georg Homuth , Roberto Lorbeer , Thorsten Reffelmann , Rainer Rettig , Uwe Völker , Pilar Galan , Ivo G Gut , Serge Hercberg , G Mark Lathrop , Diana Zelenika , Panos Deloukas , Nicole Soranzo , Frances M Williams , Guangju Zhai , Veikko Salomaa , Markku Laakso , Roberto Elosua , Nita G Forouhi , Henry Völzke , Cuno S Uiterwaal , Yvonne T van der Schouw , Mattijs E Numans , Giuseppe Matullo , Gerjan Navis , Göran Berglund , Sheila A Bingham , Jaspal S Kooner , John M Connell , Stefania Bandinelli , Luigi Ferrucci , Hugh Watkins , Tim D Spector , Jaakko Tuomilehto , David Altshuler , David P Strachan , Maris Laan , Pierre Meneton , Nicholas J Wareham , Manuela Uda , Marjo-Riitta Jarvelin , Vincent Mooser , Olle Melander , Ruth J F Loos , Paul Elliott , Gonçalo R Abecasis , Mark Caulfield , Patricia B Munroe

Structurally and functionally unique complexins at retinal ribbon synapses.

J. Cell Biol.     Kerstin Reim , Heike Wegmeyer , Johann Helmut Brandstätter , Mingshan Xue , Christian Rosenmund , Thomas Dresbach , Kay Hofmann , Nils Brose

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet.     Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano