| Type | Description |
|---|---|
| Definition | relaxin family peptide receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:58:00 | The anti-fibrotic actions of relaxin are mediated through AT2 R-associated protein phosphatases via RXFP1-AT2 R functional crosstalk in human cardiac myofibroblasts. | 32297670 |
| 2020-05-30 11:06:00 | In mice expressing human RXFP1 gene treated with carbon tetrachloride, ML290 significantly reduced collagen content, alpha-smooth muscle actin expression, and cell proliferation around portal ducts. | 31419161 |
| 2019-10-19 11:15:00 | Idiopathic pulmonary fibrosis lung fibroblasts transfected with anti-miR-144-3p had increased RXFP1 expression and reduced alpha-smooth muscle actin expression. | 30709904 |
| 2017-07-22 11:54:00 | Binding of relaxin to RXFP1 recruits G proteins with subsequent activation of adenylyl cyclase and elevation of cAMP. | 27310652 |
| 2017-04-15 10:52:00 | The decreased expression of the endometrial RLX receptor in women with implantation failures, both in vitro fertilization failure and recurrent pregnancy loss, suggests that RLX may play a crucial role in the structural and functional changes of the endometrium during the window of implantation. | 26761440 |
| Type | IDs |
|---|---|
| Synonymous | LGR7, RXFPR1 |
| Gene |
UniProtKB-ID:
RXFP1_HUMAN,
Q59H16_HUMAN,
A0A087WWV0_HUMAN,
B4DGP2_HUMAN,
B3KV27_HUMAN,
A0A0A0MT52_HUMAN
UniprotKB:
Q9HBX9,
Q59H16,
A0A087WWV0,
B4DGP2,
B3KV27,
A0A0A0MT52
UniParc:
UPI00023AD68C,
UPI000013EC4B,
UPI00005A7A04,
UPI00005BA4E0,
UPI00017A6DBF,
UPI00004F6AEB,
UPI00017A6E6E,
UPI00023AD688,
UPI000002AD3A,
UPI00005BA4E1
EMBL:
AC107219,
AY899850,
AC108017,
AK300379,
AB208943,
AF190500,
AC121161,
AK295040,
AC125489,
AY899849,
AK122647,
AK294694,
AY899848,
KF457826,
AC107056,
AC019341,
CH471056,
BC113617,
BC112142
Ensembl:
ENSG00000171509
KO:
hsa:59350
|
| Nucleutide sequences |
EMBL-CDS:
BAG62114.1,
BAG58092.1,
EAX04856.1,
AAX85198.1,
AAI13618.1,
AAG17167.1,
AAX85197.1,
AAI12143.1,
AAX85196.1,
BAD92180.1,
BAG57853.1,
BAG53639.1
Ensembl_TRS:
ENST00000307765,
ENST00000471616,
ENST00000343542,
ENST00000470033,
ENST00000613319,
ENST00000423548,
ENST00000448688
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000434475,
ENSP00000345889,
ENSP00000303248,
ENSP00000420712,
ENSP00000480522,
ENSP00000405841,
ENSP00000414885
RefSeq:
NP_001240658.1,
XP_016864012.1,
XP_011530476.1,
NP_001240657.1,
XP_016864009.1,
XP_016864015.1,
XP_011530478.1,
XP_016864011.1,
NP_001240662.1,
NP_001240661.1,
XP_016864013.1,
NP_001350705.1,
XP_011530481.1,
NP_001240659.1,
XP_016864006.1,
XP_016864008.1,
NP_001240656.1,
XP_016864014.1,
XP_016864007.1,
XP_011530477.1,
NP_067647.2
|
| Others |
UniRef100:
UniRef100_Q59H16,
UniRef100_A0A087WWV0,
UniRef100_B3KV27,
UniRef100_B4DGP2,
UniRef100_A0A0A0MT52,
UniRef100_Q9HBX9
UniRef90:
UniRef90_A0A096MM05,
UniRef90_Q9HBX9,
UniRef90_Q9HBX9-5,
UniRef90_A0A2K6F1K7
UniRef50:
UniRef50_Q9HBX9,
UniRef50_F7AYQ3
UniGene:
Hs.591686
CCDS:
CCDS43276.1,
CCDS58930.1,
CCDS58929.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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