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59343 SENP2

59343

SENP2

SUMO specific peptidase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition SUMO specific peptidase 2

研究结论

Date Results Publications
2020-11-21 13:31:00 Silencing of SENP2 in Multiple Myeloma Induces Bortezomib Resistance by Activating NF-kappaB Through the Modulation of IkappaBalpha Sumoylation. 31964975
2020-05-09 12:48:00 Overexpression of SENP2 was correlated with a better overall survival of the Gastric Cancer patients with a marginally significance, indicating that SENP2 expression could be used as a novel biomarker to predict patient prognosis. 30997579
2019-10-12 10:54:00 SENP2 regulates its substrate for desumoylation, and also the role of SENP2 in TGF-beta induced cancer cell migration. 29955155
2019-04-06 12:45:00 he nuclear factor (NF)kappaB signaling pathway was also regulated by the overexpression of SENP2. On the whole, the findings of this study indicate tha SENP2 can act as a tumor suppressor in CLL cells, and may thus prove to be a novel target for CLL treatment in clinical practice. 30431078
2019-03-30 11:06:00 SENP2 is amplified as part of the chromosome 3q amplification in many cancers and Increased SENP2 expression prolongs MDC1 focus retention and increases NHEJ and radioresistance 30796017

名称对应

Type IDs
Synonymous AXAM2, SMT3IP2
Gene
UniProtKB-ID: SENP2_HUMAN
UniprotKB: Q9HC62
UniParc: UPI00017A78FC, UPI000007452F
EMBL: AK027599, AK298628, AF151697, AC133473, BC040609, AL834380, AC016961, AB037752
Ensembl: ENSG00000163904
KO: hsa:59343
Nucleutide sequences
EMBL-CDS: BAA92569.2, AAG15309.2, BAB55222.1, BAG60804.1, AAH40609.1, CAD39043.1
Ensembl_TRS: ENST00000296257
Protein sequencees
Ensembl_PRO: ENSP00000296257
RefSeq: XP_005247747.2, XP_005247748.1, XP_016862462.1, NP_067640.2
Others
UniRef100: UniRef100_Q9HC62
UniRef90: UniRef90_Q9HC62
UniRef50: UniRef50_Q9HC62
UniGene: Hs.401388
CCDS: CCDS33902.1

全选

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