| Type | Description |
|---|---|
| Definition | transient receptor potential cation channel subfamily V member 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:13:00 | Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflow. | 33226641 |
| 2021-04-13 10:10:00 | The structural changes of the mutated ankyrin repeat domain of the human TRPV4 channel alter its ATP binding ability. | 31493693 |
| 2021-04-03 13:29:00 | TRPV4: A Physio and Pathophysiologically Significant Ion Channel. | 32481620 |
| 2021-03-20 13:35:00 | Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension. | 33664271 |
| 2021-03-06 13:34:00 | TRPV4 Inhibition and CRISPR-Cas9 Knockout Reduce Inflammation Induced by Hyperphysiological Stretching in Human Annulus Fibrosus Cells. | 32708074 |
| Type | IDs |
|---|---|
| Synonymous | BCYM3, CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VRL2, VROAC |
| Gene |
UniProtKB-ID:
TRPV4_HUMAN
UniprotKB:
Q9HBA0
UniParc:
UPI0000141056,
UPI00005EE241,
UPI000000D75C,
UPI000003BB44,
UPI00005EE240,
UPI00005EE242
EMBL:
AF279673,
AF263523,
AB032427,
DQ059644,
DQ059646,
DQ059645,
CH471054,
AF258465,
AB073669,
BC117426,
BC143315,
AB100308,
AJ296305
Ensembl:
ENSG00000111199
KO:
hsa:59341
|
| Nucleutide sequences |
EMBL-CDS:
AAG28029.1,
AAI43316.1,
BAC06573.1,
BAC55864.1,
AAZ04919.1,
CAC82937.1,
EAW97879.1,
BAB69040.1,
AAK69487.1,
AAZ04920.1,
AAI17427.1,
AAZ04918.1,
AAG16127.1
Ensembl_TRS:
ENST00000261740,
ENST00000537083,
ENST00000536838,
ENST00000418703,
ENST00000544971,
ENST00000541794
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000442167,
ENSP00000261740,
ENSP00000444336,
ENSP00000442738,
ENSP00000406191,
ENSP00000443611
RefSeq:
NP_001170899.1,
XP_011536935.2,
XP_016875263.1,
NP_067638.3,
NP_671737.1,
XP_011536936.2,
XP_005253975.1,
XP_011536933.2,
XP_011536934.2,
XP_011536932.2,
XP_011536937.1,
NP_001170902.1,
NP_001170904.1
|
| Others |
UniRef100:
UniRef100_Q9HBA0
UniRef90:
UniRef90_Q9HBA0
UniRef50:
UniRef50_Q9HBA0
UniGene:
Hs.506713
CCDS:
CCDS53828.1,
CCDS53827.1,
CCDS9135.1,
CCDS53829.1,
CCDS9134.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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