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59340 HRH4

59340

HRH4

histamine receptor H4

protein-coding

Homo sapiens

基因描述

Type Description
Definition histamine receptor H4

研究结论

Date Results Publications
2020-10-24 14:00:00 Study of the antitumour effects and the modulation of immune response by histamine in breast cancer. 31748740
2020-01-04 10:48:00 HRH4 rs77485247 polymorphism may be an important mediator in regulating proinflammatory cytokines 31133025
2019-11-02 10:42:00 our present study confirmed the expression of H4R in ESCC, which was closely associated with clinicopathological features, including histological grades, primary tumor size, lymph node metastasis, and patient survival. 30058054
2019-10-12 10:50:00 ur data indicate that the H4 peptide tail promotes the formation of active strand transfer complexes (STCs) and support an activation step of the incoming intasome at the contact of the histone tail. 30767014
2018-12-01 11:06:00 these findings reveal that rs11662595 is a loss-of-function polymorphism that results in dysfunction of HRH4 and attenuates the anti-epithelial-to-mesenchymal transition function of HRH4 in non-small cell lung cancer (NSCLC), which provides a promising biomarker for prognosis and therapy of NSCLC. 28847511

名称对应

Type IDs
Synonymous AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R
Gene
UniProtKB-ID: HRH4_HUMAN, B2KJ49_HUMAN
UniprotKB: Q9H3N8, B2KJ49
UniParc: UPI0001740518, UPI0000039A92, UPI0001740519
EMBL: AF312230, BC112348, CH471088, AB045370, AC007922, DQ835187, EF444982, BC069136, AB044934, AF325356, AF329449, AF307973, AJ298292, AY136745, DQ835186
Ensembl: ENSG00000134489
KO: hsa:59340
Nucleutide sequences
EMBL-CDS: BAB20091.1, AAH69136.1, AAI12349.1, ABI54174.1, ACA05997.1, AAL01684.1, AAN01271.1, EAX01189.1, AAG32052.1, AAK43542.1, AAK12081.1, CAC83493.1, BAB13698.1, ABI54175.1
Ensembl_TRS: ENST00000426880, ENST00000256906
Protein sequencees
Ensembl_PRO: ENSP00000256906, ENSP00000402526
RefSeq: NP_001153638.1, NP_067637.2, NP_001137300.1
Others
UniRef100: UniRef100_B2KJ49, UniRef100_Q9H3N8
UniRef90: UniRef90_Q9H3N8, UniRef90_B2KJ49
UniRef50: UniRef50_A0A452QKW1, UniRef50_Q9H3N8
UniGene: Hs.287388
CCDS: CCDS45841.1, CCDS11887.1

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