| Type | Description |
|---|---|
| Definition | pleckstrin homology domain containing A1 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-08 10:21:00 | investigated the association of PLEKHA1 958A/G, polymorphisms with Age-Related Macular Degeneration (AMD) risk. PLEKHA1 958A/G polymorphism was associated with a decreased AMD risk (additive model: aOR=0.722, 95% CI=0.450-0.979, P=0.019; allele model: aOR=0.883, 95% CI=0.736-0.992, P=0.014) | 29565837 |
| 2016-04-23 11:55:00 | Studies indicate that the high-risk allele of the 10q26 locus encompasses three genes, PLEKHA1, ARMS2, and HTRA1 with high linkage disequilibrium. | 26427389 |
| 2015-05-16 10:08:00 | CX3CR1 (T280M and V249I) and PLEKHA1 (A320T) polymorphisms were not found to be associated with age-related macular degeneration in an Indian population. | 25050486 |
| 2014-06-14 13:24:00 | This study provides evidence of the joint contribution of genetic variants in PLEKHA1/ARMS2/HTRA1 to age-related macular degeneration risk. | 24013816 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator) | 19948975 |
| Type | IDs |
|---|---|
| Synonymous | TAPP1 |
| Gene |
UniProtKB-ID:
PKHA1_HUMAN,
Q5RGS4_HUMAN,
B3KQL5_HUMAN
UniprotKB:
Q9HB21,
Q5RGS4,
B3KQL5
UniParc:
UPI00001A841E,
UPI000015D928,
UPI000000D9DC,
UPI00003D05D2
EMBL:
BX842242,
CH471066,
AK075159,
BX664700,
BC001136,
AK057463,
BC042458,
AF286160
Ensembl:
ENSG00000107679
KO:
hsa:59338
|
| Nucleutide sequences |
EMBL-CDS:
EAW49315.1,
AAG15197.1,
BAG51917.1,
EAW49318.1,
EAW49319.1,
AAH01136.1,
EAW49316.1,
AAH42458.1,
BAG52077.1
Ensembl_TRS:
ENST00000368988,
ENST00000368990,
ENST00000392799,
ENST00000433307,
ENST00000368989
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376547,
ENSP00000394416,
ENSP00000357984,
ENSP00000357986,
ENSP00000357985
RefSeq:
NP_001364182.1,
NP_001364180.1,
XP_016871976.1,
NP_001364185.1,
XP_016871967.1,
XP_011538321.1,
XP_016871969.1,
NP_001364170.1,
NP_001364164.1,
NP_001364174.1,
XP_011538324.1,
NP_001364187.1,
NP_001364167.1,
XP_011538319.1,
XP_016871968.1,
NP_001364172.1,
XP_016871972.1,
XP_016871979.1,
NP_001364166.1,
NP_001001974.1,
NP_067635.2,
NP_001364163.1,
NP_001364175.1,
NP_001364176.1,
NP_001364184.1,
XP_016871978.1,
NP_001364178.1,
NP_001364169.1,
XP_016871970.1,
NP_001364171.1,
XP_016871973.1,
NP_001364160.1,
NP_001364181.1,
XP_024303875.1,
NP_001364179.1,
XP_024303883.1,
XP_024303882.1,
XP_024303877.1,
XP_011538323.1,
XP_024303878.1,
NP_001364159.1,
NP_001317107.1,
NP_001364177.1,
XP_024303876.1,
NP_001182537.1,
NP_001364161.1,
XP_016871971.1,
XP_024303881.1,
NP_001364183.1,
XP_011538320.1,
NP_001364173.1,
XP_011538326.1,
NP_001364186.1,
XP_024303879.1,
XP_016871975.1
|
| Others |
UniRef100:
UniRef100_Q9HB21,
UniRef100_Q5RGS4
UniRef90:
UniRef90_Q8BUL6,
UniRef90_Q9HB21
UniRef50:
UniRef50_Q9HB21
UniGene:
Hs.643512,
Hs.738826
CCDS:
CCDS55730.1,
CCDS7629.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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