| Type | Description |
|---|---|
| Definition | adenylate cyclase 10 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 10:49:00 | the sAC( type 10 soluble adenylyl cyclase)-EPAC axis may regulate basal and induced AMPK activity and support mitophagy, cellular energy and redox homeostasis. The study argues for sAC as a potential target in treating pathologies associated with AMPK downregulation | 31172217 |
| 2013-09-28 11:24:00 | within the pulmonary circulation, AC10 is expressed in pulmonary microvascular endothelial cells (PMVECs) and pulmonary artery endothelial cells (PAECs), yet expression in PAECs is lower. | 23686854 |
| 2012-12-08 11:21:00 | activation of sAC in the pancreatic acinar cell has a protective effect and reduces the pathologic activation of proteases during pancreatitis | 22844459 |
| 2012-05-26 11:08:00 | a key role of soluble adenylyl cyclase in simulated in vitro ischaemia induced mitochondrial Bax translocation and activation of the mitochondrial pathway of apoptosis in adult cardiomyocytes. | 22106416 |
| 2010-01-21 00:00:00 | description of a novel pathway for pH regulation linking the bicarbonate activated soluble adenylyl cyclase to the vacuolar H+ATPase | 14512417 |
| Type | IDs |
|---|---|
| Synonymous | Sac |
| Gene |
UniProtKB-ID:
ADCYA_RAT
UniprotKB:
Q9Z286
UniParc:
UPI00000E63A7
EMBL:
AF081941
Ensembl:
ENSRNOG00000053410
KO:
rno:59320
|
| Nucleutide sequences |
EMBL-CDS:
AAD04035.1
Ensembl_TRS:
ENSRNOT00000082677
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000072356
RefSeq:
XP_008767900.1,
XP_008767901.1,
XP_008767899.1,
NP_067716.1,
XP_008767902.1
|
| Others |
UniRef100:
UniRef100_Q9Z286
UniRef90:
UniRef90_Q9Z286
UniRef50:
UniRef50_Q96PN6
UniGene:
Rn.42892
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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