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5932 RBBP8

5932

RBBP8

RB binding protein 8, endonuclease

protein-coding

Homo sapiens

基因描述

Type Description
Definition RB binding protein 8, endonuclease

研究结论

Date Results Publications
2021-03-27 14:44:00 SCF(SKP2) regulates APC/C(CDH1)-mediated degradation of CTIP to adjust DNA-end resection in G2-phase. 32683422
2021-02-06 13:55:00 SUMOylation mediates CtIP's functions in DNA end resection and replication fork protection. 33406258
2021-02-06 13:53:00 Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability. 32379725
2020-11-28 13:15:00 RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer. 31636387
2020-10-24 14:11:00 Phosphorylated CtIP bridges DNA to promote annealing of broken ends. 32817418

名称对应

Type IDs
Synonymous COM1, CTIP, JWDS, RIM, SAE2, SCKL2
Gene
UniProtKB-ID: CTIP_HUMAN, A0A024RC34_HUMAN
UniprotKB: Q99708, A0A024RC34
UniParc: UPI000013D1A9, UPI000258D138, UPI0000252190
EMBL: AK292481, AC091147, BX648221, AF043431, AC106033, CH471088, BC030590, U72066
Ensembl: ENSG00000101773
KO: hsa:5932
Nucleutide sequences
EMBL-CDS: AAH30590.1, BAF85170.1, AAC14371.1, AAC34368.1, EAX01144.1, EAX01145.1, EAX01143.1, EAX01146.1
Gene_ORFName: hCG_37754
Ensembl_TRS: ENST00000327155, ENST00000399725, ENST00000399722
Protein sequencees
Ensembl_PRO: ENSP00000382630, ENSP00000382628, ENSP00000323050
RefSeq: XP_006722583.1, XP_006722584.1, XP_005258383.1, XP_016881405.1, NP_976036.1, XP_011524434.1, NP_002885.1, XP_005258382.1, XP_006722582.1, XP_024307001.1, NP_976037.1
Others
UniRef100: UniRef100_Q99708
UniRef90: UniRef90_Q99708
UniRef50: UniRef50_Q99708
UniGene: Hs.546282
CCDS: CCDS11875.1, CCDS11874.1

全选

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