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5926 ARID4A

5926

ARID4A

AT-rich interaction domain 4A

protein-coding

Homo sapiens

基因描述

Type Description
Definition AT-rich interaction domain 4A

研究结论

Date Results Publications
2019-10-26 10:26:00 ARID4A and ARID4B may play the role as tumor suppressor gene in prostate cancer by inhibiting cell proliferation, migration, and invasion. Moreover, co-downregulation of ARID4A and ARID4B can predict poorer prognosis in prostate cancer, suggesting they might be the novel marker of prognosis and potential therapeutic targets for prostate cancer in human. 29797600
2018-03-17 11:00:00 Consistently, our ITC assays also showed that DNA does not significantly enhance the histone binding ability of the chromo barrel domain of RBBP1. 29408527
2014-04-26 12:59:00 The RBBP1 Tudor domain binds both double- and single-stranded DNA with an affinity of 10-100 muM; no apparent DNA sequence specificity was detected. 24379399
2012-12-22 10:47:00 ARID4a (AT-rich interacting domain 4a, also known as RBP1) and CCL5 (C-C motif ligand 5) are targets for miR-302. 22732186
2012-05-05 10:04:00 chromobarrel domain of RBBP1 is responsible for recognizing methylated histone tails in chromatin remodeling and epigenetic regulation 22247551

名称对应

Type IDs
Synonymous RBBP-1, RBBP1, RBP-1, RBP1
Gene
UniProtKB-ID: ARI4A_HUMAN, Q05CG0_HUMAN, A0A024R657_HUMAN, A0A024R680_HUMAN, A0A024R6A2_HUMAN
UniprotKB: P29374, Q05CG0, A0A024R657, A0A024R680, A0A024R6A2
UniParc: UPI000013FD01, UPI000013D14D, UPI0000D49AAD, UPI000013D14C
EMBL: BC026230, S66427, S57160, S57153, CH471061, S57162, AL132989, AL139021
Ensembl: ENSG00000032219
KO: hsa:5926
Nucleutide sequences
EMBL-CDS: AAB25834.1, AAB25835.2, AAB28543.1, AAB25833.1, AAH26230.1, EAW80732.1, EAW80731.1, EAW80729.1, EAW80728.1, EAW80730.1, EAW80727.1
Gene_ORFName: hCG_20985, hCG_20985, hCG_20985
Ensembl_TRS: ENST00000355431, ENST00000431317, ENST00000348476, ENST00000395168
Protein sequencees
Ensembl_PRO: ENSP00000347602, ENSP00000344556, ENSP00000397368, ENSP00000378597
RefSeq: XP_016877053.1, NP_075377.2, NP_002883.3, XP_016877049.1, XP_005268021.1, XP_016877050.1, XP_016877054.1, XP_024305451.1, XP_005268022.1, XP_016877051.1, XP_024305452.1, XP_016877052.1, NP_075376.2
Others
UniRef100: UniRef100_Q05CG0, UniRef100_A0A024R680, UniRef100_A0A024R6A2, UniRef100_P29374
UniRef90: UniRef90_P29374, UniRef90_Q05CG0, UniRef90_A0A024R6A2, UniRef90_A0A024R680
UniRef50: UniRef50_A0A673J6C5, UniRef50_P29374, UniRef50_A0A0D9RPL2
UniGene: Hs.161000
CCDS: CCDS45114.1, CCDS9733.1, CCDS9732.1

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