| Type | Description |
|---|---|
| Definition | Ras protein specific guanine nucleotide releasing factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 14:37:00 | AnxA6 may be a reliable biomarker for distant relapse-free survival and response of triple negative breast cancer (TNBC) patients to chemotherapy, and that the reciprocal expression of AnxA6 and GRF2 can reliably delineate TNBCs into rapidly growing and invasive subsets which may be more relevant for subset-specific therapeutic interventions. | 32298357 |
| 2020-07-04 11:34:00 | High RASGRF2 expression is associated with migration and invasion of colorectal cancer. | 30359168 |
| 2018-11-17 10:56:00 | RASGRF2-int is significantly associated with drug addiction. | 30249655 |
| 2017-07-01 12:19:00 | this genetic association study represents the first to show an association of the RASGRF2 G>A (rs26907) polymorphism with Alcoholic Liver Cirrhosis in men, particularly in the subgroup of patients with alcohol dependence. The findings suggest the potential relevance of the RAS gene family in alcoholism and Alcoholic Liver Cirrhosis. | 27992614 |
| 2017-06-24 12:40:00 | Endoplasmic reticulum stress triggers a localized signaling module on the ER surface involving Nox4-dependent calcium mobilization, which directs local Ras activation through ER-associated, calcium-responsive RasGRF. | 27856453 |
| Type | IDs |
|---|---|
| Synonymous | GRF2, RAS-GRF2 |
| Gene |
UniProtKB-ID:
RGRF2_HUMAN,
Q68DX5_HUMAN,
A0A2X0SFL3_HUMAN
UniprotKB:
O14827,
Q68DX5,
A0A2X0SFL3
UniParc:
UPI0000047ABF,
UPI000041A081
EMBL:
LS482416,
CH471084,
CR749239,
AF181250,
AF023130,
BC136296,
BC126112
Ensembl:
ENSG00000113319
KO:
hsa:5924
|
| Nucleutide sequences |
EMBL-CDS:
AAI36297.1,
AAB80953.1,
AAI26113.1,
EAW95863.1,
AAD55268.1,
CAH18095.1,
SPT35793.1
Ensembl_TRS:
ENST00000265080
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265080
RefSeq:
XP_005248622.1,
XP_024301909.1,
NP_008840.1,
XP_016865171.1,
XP_016865172.1,
XP_024301910.1
|
| Others |
UniRef100:
UniRef100_O14827
UniRef90:
UniRef90_O14827
UniRef50:
UniRef50_O14827
UniGene:
Hs.162129
CCDS:
CCDS4052.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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