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5923 RASGRF1

5923

RASGRF1

Ras protein specific guanine nucleotide releasing factor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition Ras protein specific guanine nucleotide releasing factor 1

研究结论

Date Results Publications
2018-09-22 10:59:00 Low RASGRF1 expression due to hypermethylation is associated with Colorectal Cancer. 29530990
2018-06-23 11:20:00 Our studies have shown that the heritability of myopia makes 66.4% in Lithuania. We detected significant associations between the combinations of GJD2 CC and RASGRF1 GT and odds ratio of developing myopia. 29793445
2017-12-23 12:21:00 genetic variants in BICC1 and RASGRF1 are closely associated with high myopia, which appears to be a potential candidate for high myopia in Chinese Han population. 29044055
2017-06-24 12:40:00 Endoplasmic reticulum stress triggers a localized signaling module on the ER surface involving Nox4-dependent calcium mobilization, which directs local Ras activation through ER-associated, calcium-responsive RasGRF. 27856453
2017-02-18 10:56:00 Data show that microRNA miR-137 directly recognized the 3'-UTR (3'-untranslated region) of the RASGRF1 (Ras protein-specific guanine nucleotide-releasing factor 1) transcript and regulated RASGRF1 expression. 26440052

名称对应

Type IDs
Synonymous CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1
Gene
UniProtKB-ID: RGRF1_HUMAN, Q8IUU5_HUMAN, A8K270_HUMAN
UniprotKB: Q13972, Q8IUU5, A8K270
UniParc: UPI00015DA5F9, UPI00001FE9CD, UPI0000074701, UPI000002F89F, UPI000013D1F1
EMBL: L26584, M91815, S62035, AK226101, CH471136, AK290135, AC011944, BC040275, AC104231
Ensembl: ENSG00000058335
KO: hsa:5923
Nucleutide sequences
EMBL-CDS: AAB26881.1, EAW99141.1, AAA58417.1, EAW99142.1, AAH40275.1, BAF82824.1
Gene_ORFName: hCG_23727
Ensembl_TRS: ENST00000558480, ENST00000419573, ENST00000394745
Protein sequencees
Ensembl_PRO: ENSP00000452781, ENSP00000405963, ENSP00000378228
RefSeq: XP_016877944.1, NP_002882.3, XP_016877948.1, XP_016877947.1, XP_011520168.1, XP_011520169.1, NP_001139120.1, XP_016877945.1, NP_722522.1, XP_016877946.1
Others
UniRef100: UniRef100_A8K270, UniRef100_Q13972, UniRef100_Q8IUU5
UniRef90: UniRef90_Q13972, UniRef90_Q8IUU5, UniRef90_A8K270
UniRef50: UniRef50_P28818, UniRef50_A0A060WTB6, UniRef50_Q13972
UniGene: Hs.459035
CCDS: CCDS10309.1, CCDS42065.1, CCDS45320.1

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