| Type | Description |
|---|---|
| Definition | Mitochondrial calcium uniporter |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 12:11:00 | MCU knockout flies are short lived compared to EMRE or MICU3 mutants. MCU loss blocks fast mitochondrial calcium uptake. | 31042479 |
| 2018-06-11 01:02:00 | These results reveal an in vivo developmental role for the mitochondrial uniporter complex in establishing the necessary structural and functional neuronal substrates for normal memory formation in the adult organism. | 27568554 |
| 2017-09-30 11:31:00 | Data suggest that MCU plays key role in endoplasmic reticulum-to-mitochondrial calcium transfer and for cell death due to mitochondrial dysfunction under oxidative stress. | 28726639 |
| Type | IDs |
|---|---|
| Synonymous | CG18769, CG8352, Dmel\CG18769, dMCU1 |
| Gene |
UniProtKB-ID:
MCU_DROME
UniprotKB:
Q8IQ70
UniParc:
UPI000007880B,
UPI0001E30FFA,
UPI000034DED8,
UPI000237F57C,
UPI0003954CA7
EMBL:
BT125673,
AY051736,
AE014296,
AY122129
EnsemblGenome:
FBgn0042185
KO:
dme:Dmel_CG18769
|
| Nucleutide sequences |
EMBL-CDS:
AAS65071.1,
AFH04318.1,
ADN90233.1,
AAK93160.1,
AAS65073.2,
AHN57979.1,
AAS65072.1,
AAN12083.2,
AAG22325.2,
AAN12082.2,
AAM52641.1
Gene_ORFName:
CG18769
EnsemblGenome_TRS:
FBtr0076974,
FBtr0076971,
FBtr0076973,
FBtr0076970,
FBtr0307511,
FBtr0307510,
FBtr0344294,
FBtr0076972
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0076680,
FBpp0076683,
FBpp0300165,
FBpp0076682,
FBpp0310698,
FBpp0076681,
FBpp0076679,
FBpp0300166
RefSeq:
NP_729173.1,
NP_996004.1,
NP_729174.2,
NP_001286954.1,
NP_996002.2,
NP_001246647.1,
NP_996003.1,
NP_652706.3
|
| Others |
UniRef100:
UniRef100_Q8IQ70
UniRef90:
UniRef90_Q8IQ70
UniRef50:
UniRef50_Q8IQ70
UniGene:
Dm.7990
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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