| Type | Description |
|---|---|
| Definition | RAS p21 protein activator 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 10:44:00 | Authors found that knockdown of RASA2 inhibited MTC cell proliferation. | 31298226 |
| 2019-01-26 11:55:00 | The SNP of ZBTB38-RASA2 was significantly related with the appearance of myoclonus in sporadic Creutzfeldt-Jacob disease patients. | 29216791 |
| 2016-06-28 10:30:00 | Recurrent inactivating RASA2 mutations are associated with melanoma. | 26502337 |
| 2001-09-25 10:47:00 | GAP1m is a Ras GAP that switches off Ras signalling. GAP1m undergoes a plasma membrane association following growth factor stimulation of PI 3-kinase as a result of its PH domain binding to phosphatidylinositol 3,4,5-trisphosphate. | 10074452 |
| Type | IDs |
|---|---|
| Synonymous | GAP1M |
| Gene |
UniProtKB-ID:
RASA2_HUMAN
UniprotKB:
Q15283
UniParc:
UPI0000E5A9E5,
UPI00001351F5
EMBL:
D82880,
D78155,
D82881,
AF115573,
AC010184,
AC092977,
D78156,
CH471052,
AK292016
Ensembl:
ENSG00000155903
KO:
hsa:5922
|
| Nucleutide sequences |
EMBL-CDS:
BAA11621.1,
AAD09821.1,
BAA11622.1,
BAA11231.1,
BAA11230.1,
BAF84705.1,
EAW78999.1
Ensembl_TRS:
ENST00000286364
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000286364
RefSeq:
NP_001290174.1,
NP_006497.2,
XP_016862460.1,
XP_011511361.1,
NP_001290175.1,
XP_016862459.1,
XP_024309459.1,
XP_016862458.1,
XP_016862457.1
|
| Others |
UniRef100:
UniRef100_Q15283
UniRef90:
UniRef90_Q15283
UniRef50:
UniRef50_Q15283
UniGene:
Hs.655941
CCDS:
CCDS3117.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31298226 |
Med. Sci. Monit. Mei Jiang , Xin Shi , Hua Zhu , Wu Wei , Jinyan Li |
2019-07-12 | - |
| 30196744 |
ATG5 is required for B cell polarization and presentation of particulate antigens. Autophagy Florent Arbogast , Johan Arnold , Philippe Hammann , Lauriane Kuhn , Johana Chicher , Diane Murera , Justine Weishaar , Sylviane Muller , Jean-Daniel Fauny , Frédéric Gros |
2019-02-01 | - |
| 30655611 |
WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation. Nat Commun Woo-Jeong Jeong , Jong-Chan Park , Woo-Shin Kim , Eun Ji Ro , Soung Hoo Jeon , Sang-Kyu Lee , Young Nyun Park , Do Sik Min , Kang-Yell Choi |
2019-01-17 | - |
| 29467282 |
Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. Jan B Heidelberger , Andrea Voigt , Marina E Borisova , Giuseppe Petrosino , Stefanie Ruf , Sebastian A Wagner , Petra Beli |
2018-04-01 | - |
| 29216791 |
Prion Chen Gao , Qiang Shi , Jing Wei , Wei Zhou , Kang Xiao , Jing Wang , Qi Shi , Xiao-Ping Dong |
2018-01-02 | - |
| 28611215 |
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown |
2017-06-27 | - |
| 26502337 |
Recurrent inactivating RASA2 mutations in melanoma. Nat. Genet. Rand Arafeh , Nouar Qutob , Rafi Emmanuel , Alona Keren-Paz , Jason Madore , Abdel Elkahloun , James S Wilmott , Jared J Gartner , Antonella Di Pizio , Sabina Winograd-Katz , Sivasish Sindiri , Ron Rotkopf , Ken Dutton-Regester , Peter Johansson , Antonia L Pritchard , Nicola Waddell , Victoria K Hill , Jimmy C Lin , Yael Hevroni , Steven A Rosenberg , Javed Khan , Shifra Ben-Dor , Masha Y Niv , Igor Ulitsky , Graham J Mann , Richard A Scolyer , Nicholas K Hayward , Yardena Samuels |
2015-12-01 | - |
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 23222517 |
Seventy-five genetic loci influencing the human red blood cell. Nature Pim van der Harst , Weihua Zhang , Irene Mateo Leach , Augusto Rendon , Niek Verweij , Joban Sehmi , Dirk S Paul , Ulrich Elling , Hooman Allayee , Xinzhong Li , Aparna Radhakrishnan , Sian-Tsung Tan , Katrin Voss , Christian X Weichenberger , Cornelis A Albers , Abtehale Al-Hussani , Folkert W Asselbergs , Marina Ciullo , Fabrice Danjou , Christian Dina , Tõnu Esko , David M Evans , Lude Franke , Martin Gögele , Jaana Hartiala , Micha Hersch , Hilma Holm , Jouke-Jan Hottenga , Stavroula Kanoni , Marcus E Kleber , Vasiliki Lagou , Claudia Langenberg , Lorna M Lopez , Leo-Pekka Lyytikäinen , Olle Melander , Federico Murgia , Ilja M Nolte , Paul F O'Reilly , Sandosh Padmanabhan , Afshin Parsa , Nicola Pirastu , Eleonora Porcu , Laura Portas , Inga Prokopenko , Janina S Ried , So-Youn Shin , Clara S Tang , Alexander Teumer , Michela Traglia , Sheila Ulivi , Harm-Jan Westra , Jian Yang , Jing Hua Zhao , Franco Anni , Abdel Abdellaoui , Antony Attwood , Beverley Balkau , Stefania Bandinelli , François Bastardot , Beben Benyamin , Bernhard O Boehm , William O Cookson , Debashish Das , Paul I W de Bakker , Rudolf A de Boer , Eco J C de Geus , Marleen H de Moor , Maria Dimitriou , Francisco S Domingues , Angela Döring , Gunnar Engström , Gudmundur Ingi Eyjolfsson , Luigi Ferrucci , Krista Fischer , Renzo Galanello , Stephen F Garner , Bernd Genser , Quince D Gibson , Giorgia Girotto , Daniel Fannar Gudbjartsson , Sarah E Harris , Anna-Liisa Hartikainen , Claire E Hastie , Bo Hedblad , Thomas Illig , Jennifer Jolley , Mika Kähönen , Ido P Kema , John P Kemp , Liming Liang , Heather Lloyd-Jones , Ruth J F Loos , Stuart Meacham , Sarah E Medland , Christa Meisinger , Yasin Memari , Evelin Mihailov , Kathy Miller , Miriam F Moffatt , Matthias Nauck , Maria Novatchkova , Teresa Nutile , Isleifur Olafsson , Pall T Onundarson , Debora Parracciani , Brenda W Penninx , Lucia Perseu , Antonio Piga , Giorgio Pistis , Anneli Pouta , Ursula Puc , Olli Raitakari , Susan M Ring , Antonietta Robino , Daniela Ruggiero , Aimo Ruokonen , Aude Saint-Pierre , Cinzia Sala , Andres Salumets , Jennifer Sambrook , Hein Schepers , Carsten Oliver Schmidt , Herman H W Silljé , Rob Sladek , Johannes H Smit , John M Starr , Jonathan Stephens , Patrick Sulem , Toshiko Tanaka , Unnur Thorsteinsdottir , Vinicius Tragante , Wiek H van Gilst , L Joost van Pelt , Dirk J van Veldhuisen , Uwe Völker , John B Whitfield , Gonneke Willemsen , Bernhard R Winkelmann , Gerald Wirnsberger , Ale Algra , Francesco Cucca , Adamo Pio d'Adamo , John Danesh , Ian J Deary , Anna F Dominiczak , Paul Elliott , Paolo Fortina , Philippe Froguel , Paolo Gasparini , Andreas Greinacher , Stanley L Hazen , Marjo-Riitta Jarvelin , Kay Tee Khaw , Terho Lehtimäki , Winfried Maerz , Nicholas G Martin , Andres Metspalu , Braxton D Mitchell , Grant W Montgomery , Carmel Moore , Gerjan Navis , Mario Pirastu , Peter P Pramstaller , Ramiro Ramirez-Solis , Eric Schadt , James Scott , Alan R Shuldiner , George Davey Smith , J Gustav Smith , Harold Snieder , Rossella Sorice , Tim D Spector , Kari Stefansson , Michael Stumvoll , W H Wilson Tang , Daniela Toniolo , Anke Tönjes , Peter M Visscher , Peter Vollenweider , Nicholas J Wareham , Bruce H R Wolffenbuttel , Dorret I Boomsma , Jacques S Beckmann , George V Dedoussis , Panos Deloukas , Manuel A Ferreira , Serena Sanna , Manuela Uda , Andrew A Hicks , Josef Martin Penninger , Christian Gieger , Jaspal S Kooner , Willem H Ouwehand , Nicole Soranzo , John C Chambers |
2012-12-20 | - |
| 22210626 |
Hum. Mol. Genet. Simon Mead , James Uphill , John Beck , Mark Poulter , Tracy Campbell , Jessica Lowe , Gary Adamson , Holger Hummerich , Norman Klopp , Ina-Maria Rückert , H-Erich Wichmann , Dhoyazan Azazi , Vincent Plagnol , Wandagi H Pako , Jerome Whitfield , Michael P Alpers , John Whittaker , David J Balding , Inga Zerr , Hans Kretzschmar , John Collinge |
2012-04-15 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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