| Type | Description |
|---|---|
| Definition | retinoic acid receptor responder 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:26:00 | Expression of RARRES1 and AGBL2 and progression of conventional renal cell carcinoma. | 32307444 |
| 2021-02-20 13:34:00 | Soluble RARRES1 induces podocyte apoptosis to promote glomerular disease progression. | 32634130 |
| 2020-05-30 13:13:00 | Investigated whether tazarotene-induced gene 1 protein (TIG1) affects the activity of urokinase plasminogen-type activator, which is negatively regulated by serine peptidase inhibitor Kazal type 2 (SPINK2), potentially preventing epithelial mesenchymal transition and suppressing cell migration and invasion. | 31886233 |
| 2019-05-11 12:46:00 | Study demonstrates that RARRES1 depletion in epithelial cells caused a global increase in lipid synthesis. RARRES1-depleted cells rewire glucose metabolism by switching from aerobic glycolysis to glucose-dependent de novo lipogenesis. Treatment with fatty acid synthase inhibitor reversed the effects of RARRES1 depletion. | 30557378 |
| 2018-11-17 12:32:00 | TIG1 interacted with DNAJC8 in the cytosol, and this interaction completely blocked DNAJC8-mediated PKM2 translocation and inhibited glucose uptake. Furthermore, increased glycose uptake was observed in cells in which TIG1 was silenced. | 29902837 |
| Type | IDs |
|---|---|
| Synonymous | LXNL, PERG-1, TIG1 |
| Gene |
UniProtKB-ID:
TIG1_HUMAN
UniprotKB:
P49788
UniParc:
UPI0000352C77,
UPI000006E088
EMBL:
BC029640,
U27185
Ensembl:
ENSG00000118849
KO:
hsa:5918
|
| Nucleutide sequences |
EMBL-CDS:
AAH29640.1,
AAA99722.1
Ensembl_TRS:
ENST00000479756,
ENST00000237696
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418556,
ENSP00000237696
RefSeq:
NP_002879.2,
XP_005247743.3,
NP_996846.1
|
| Others |
UniRef100:
UniRef100_P49788
UniRef90:
UniRef90_P49788
UniRef50:
UniRef50_P49788
UniGene:
Hs.131269
CCDS:
CCDS3184.1,
CCDS54665.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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