| Type | Description |
|---|---|
| Definition | NIMA (never in mitosis gene a)-related expressed kinase 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:59:00 | NEK7 mediated assembly and activation of NLRP3 inflammasome downstream of potassium efflux in ventilator-induced lung injury. | 32353421 |
| 2020-09-05 13:53:00 | NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-kappaB signaling. | 31787755 |
| 2019-12-14 12:13:00 | NEK7-deficient PV+ interneurons show altered microtubule dynamics, axon growth cone steering and reduced axon length, arbor complexity, and total number of synaptic contacts formed with pyramidal cells. | 30067978 |
| 2018-12-22 11:21:00 | NEK7 regulates dendrite morphogenesis in vitro and in vivo. NEK7 kinase activity is required for dendrite growth and branching, as well as spine formation and morphology. NEK7 regulates these processes in part through phosphorylation of the kinesin Eg5/KIF11, promoting its accumulation on microtubules in distal dendrites. | 29899413 |
| 2016-07-16 11:13:00 | NEK7 serves as a cellular switch that enforces mutual exclusivity of the inflammasome response and cell division. | 26642356 |
| Type | IDs |
|---|---|
| Synonymous | 2810460C19Rik, AU020186 |
| Gene |
UniProtKB-ID:
NEK7_MOUSE,
Q3TN15_MOUSE
UniprotKB:
Q9ES74,
Q3TN15
UniParc:
UPI0000027765,
UPI00005B2175
EMBL:
AK035502,
AK088173,
AC118216,
AC161436,
BC037697,
AK165583,
AK149308,
AF217650
Ensembl:
ENSMUSG00000026393
KO:
mmu:59125
|
| Nucleutide sequences |
EMBL-CDS:
BAC29080.1,
BAE28804.1,
AAG16652.1,
BAC40190.1,
AAH37697.1,
BAE38274.1
Ensembl_TRS:
ENSMUST00000187407,
ENSMUST00000186017,
ENSMUST00000027642
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000140635,
ENSMUSP00000140903,
ENSMUSP00000027642
RefSeq:
NP_001298077.1,
NP_067618.1
|
| Others |
UniRef100:
UniRef100_Q9ES74,
UniRef100_Q3TN15
UniRef90:
UniRef90_Q9ES74,
UniRef90_A0A2K6RTZ1
UniRef50:
UniRef50_A0A2K6RTZ1,
UniRef50_Q8TDX7
UniGene:
Mm.143817
CCDS:
CCDS15332.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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