| Type | Description |
|---|---|
| Definition | RAP2B, member of RAS oncogene family |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:19:00 | High RAP2B expression is associated with glioma. | 30997639 |
| 2019-11-23 10:57:00 | Coxiella burnetii is a Gram negative bacterium that survives and grows in a large Coxiella replicative vacuole (CRV), which displays lysosomal and autophagic features. This report presents evidence that both, EPAC and its downstream effector Rap2b, were recruited to the CRV. Rap2b wt inhibited the fusion of early Coxiella phagosomes with the fully developed CRV. | 30763357 |
| 2019-02-09 10:48:00 | Low RAP2B expression is associated with Osteosarcoma Progression. | 28409547 |
| 2018-08-18 11:44:00 | Rap2B was overexpressed in cervical cancer tissues and cell lines and knockdown of Rap2B inhibited cervical cancer cell proliferation, migration, and invasion in vitro and suppressed cervical cancer cell growth and metastasis in vivo | 28390112 |
| 2017-07-29 12:57:00 | these results revealed that Rap2B promotes renal cell carcinoma angiogenesis via phosphoinositide 3-kinase/AKT/vascular endothelial growth factor signaling pathway, which suggests that Rap2B is a novel therapeutic target for renal cell carcinoma anti-angiogenesis therapy. | 28691643 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RAP2B_HUMAN
UniprotKB:
P61225
UniParc:
UPI0000004042
EMBL:
X52987,
BC012362,
AF493915
Ensembl:
ENSG00000181467
KO:
hsa:5912
|
| Nucleutide sequences |
EMBL-CDS:
AAH12362.1,
CAA37178.1,
AAM12629.1
Ensembl_TRS:
ENST00000323534
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000319096
RefSeq:
NP_002877.2
|
| Others |
UniRef100:
UniRef100_P61225
UniRef90:
UniRef90_P61225
UniRef50:
UniRef50_P61225
UniGene:
Hs.98643,
Hs.700713
CCDS:
CCDS3170.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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