| Type | Description |
|---|---|
| Definition | argonaute RISC catalytic component 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:14:00 | The partial loss-of-function of AGO2 in mature brown adipocytes is sufficient to lead to a diminished expression of UCP1 associated to a decreased uncoupled respiration. The downregulation of AGO2 in mature brown adipocytes induces a phenotype compatible with decreased thermogenic activity. | 31152866 |
| 2019-01-26 12:33:00 | Using rat hippocampal neurons, this study reports that dendritic Ago2 is down-regulated by the proteasome upon NMDA receptor activation. | 29735530 |
| 2018-12-22 11:17:00 | Knockdown (KD) of AUF1 resulted in (1) transient upregulation of the mRNA level as well as an advancement of translation onset time (TOT) from 6 to 5 h post-serum addition, (2) loss of miRNA loading on AGO1 and AGO2 and (3) reduction in the level of AGO-1 and AGO-2 bound mRNA. | 30207314 |
| 2016-09-17 11:22:00 | Neuronal differentiation activates the p38 signaling necessary for the phosphorylation of Ago2. | 26858302 |
| 2016-08-13 12:18:00 | In rat spermatogenic cells AGO2 colocalizes with the lysosomal membrane protein LAMP2 in small vesicles that contact and surround chromatoid bodies. | 27029769 |
| Type | IDs |
|---|---|
| Synonymous | Eif2c2 |
| Gene |
UniProtKB-ID:
AGO2_RAT
UniprotKB:
Q9QZ81
UniParc:
UPI000021FC80
EMBL:
AF195534
KO:
rno:59117
|
| Nucleutide sequences |
EMBL-CDS:
AAF12800.1
|
| Protein sequencees |
RefSeq:
NP_067608.1
|
| Others |
UniRef100:
UniRef100_Q9QZ81
UniRef90:
UniRef90_Q8CJG0
UniRef50:
UniRef50_Q9UKV8
UniGene:
Rn.234328
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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