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59103 Ptges

59103

Ptges

prostaglandin E synthase

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition prostaglandin E synthase

研究结论

Date Results Publications
2019-10-19 11:26:00 In conclusion, microsomal PGES-1 plays a critical role in the continuous suppression of motor function in the post-bowel obstruction state. 29891860
2016-05-07 10:51:00 Suggest pivotal role of COX-2-mPGES-1-PGE2 axis in vascular calcification. Inhibition of COX-2 or mPGES-1 may increase the risk of calcification and subsequent adverse cardiovascular events during chronic renal failure. 26543101
2013-07-13 13:07:00 Using metabolic profiling and exploratory rat toxicity studies, a new and active mPGES-1 inhibitor with improved margins to chemically induced kidney toxicity in rats has been identified. 23284082
2012-12-08 10:59:00 Cyclooxygenase-2, not microsomal prostaglandin E synthase-1, is the mechanism for interleukin-1beta-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets 22822059
2012-09-29 11:26:00 Suggest that COX-2 and PGES, and in turn PGE(2), might play important roles in follicular cell proliferation but do not affect tumor induction in N-bis(2-hydroxypropyl)nitrosamine-induced thyroid carcinogenesis model. 22387750

名称对应

Type IDs
Synonymous Pges
Gene
UniProtKB-ID: PTGES_RAT
UniprotKB: Q9JHF3
UniParc: UPI00000E80DE
EMBL: CH474001, AF280967, AB048730, AB041998, AB035145, AC125306, BC105858
KO: rno:59103
Nucleutide sequences
EMBL-CDS: BAB20597.1, AAG24803.1, BAA96084.1, EDL93288.1, BAA95808.1, AAI05859.1
Protein sequencees
RefSeq: NP_067594.1
Others
UniRef100: UniRef100_Q9JHF3
UniRef90: UniRef90_Q9JM51
UniRef50: UniRef50_Q9JM51
UniGene: Rn.7730

全选

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研究热度

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