| Type | Description |
|---|---|
| Definition | Erbb2 interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 10:54:00 | Tumor organoids derived from Erbin/Apc double knockout mice displayed increased tumor initiation potential and activation of Wnt signaling | 29980571 |
| 2016-06-04 11:44:00 | Overexpression of FHL2 alone had no effect on Erbin expression, but in the presence of MITF, Erbin expression was decreased. | 26025865 |
| 2015-08-22 10:30:00 | By degrading Erbin and Nrf2, Sag activates the Ras-Raf pathway and causes accumulation to trigger autophagy and senescence | 26056141 |
| 2015-07-25 10:27:00 | Erbin promotes tumourigenesis and tumour growth in colorectal cancer by stabilizing epidermal growth factor receptor | 25521828 |
| 2015-04-04 11:29:00 | Results support that hyperglycemia may impair NRG1/Erb B2 signaling by disrupting the balance between NRG1 isoforms, decreasing the expression of erbin and correspondingly activating the MAPK pathway | 24252174 |
| Type | IDs |
|---|---|
| Synonymous | 1700028E05Rik, Erbb2ip, mKIAA1225 |
| Gene |
UniProtKB-ID:
ERBIN_MOUSE,
B7ZNX6_MOUSE,
B2RUK2_MOUSE,
B2RUJ2_MOUSE
UniprotKB:
Q80TH2,
B7ZNX6,
B2RUK2,
B2RUJ2
UniParc:
UPI00001E8005,
UPI000189A963,
UPI0000451CB0,
UPI00001E8000,
UPI0000451CAF
EMBL:
AK051733,
AK029054,
BC145498,
BC141178,
BC028256,
AK122473,
CT009728,
BC005691,
AC154310,
BC141188,
AF263743
Ensembl:
ENSMUSG00000021709
KO:
mmu:59079
|
| Nucleutide sequences |
EMBL-CDS:
BAC34742.1,
AAH28256.1,
AAF77047.1,
BAC26267.1,
AAH05691.3,
BAC65755.1,
AAI45499.1,
AAI41189.1,
AAI41179.1
Ensembl_TRS:
ENSMUST00000091269,
ENSMUST00000191275,
ENSMUST00000022222,
ENSMUST00000053927,
ENSMUST00000169083,
ENSMUST00000188997
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022222,
ENSMUSP00000057956,
ENSMUSP00000140536,
ENSMUSP00000088813,
ENSMUSP00000127607,
ENSMUSP00000140931
RefSeq:
NP_001005868.1,
NP_001276402.1,
NP_001276403.1,
NP_001276404.1
|
| Others |
UniRef100:
UniRef100_B2RUK2,
UniRef100_B2RUJ2,
UniRef100_B7ZNX6,
UniRef100_Q80TH2
UniRef90:
UniRef90_Q80TH2,
UniRef90_B2RUK2,
UniRef90_B2RUJ2
UniRef50:
UniRef50_Q96RT1
UniGene:
Mm.277354
CCDS:
CCDS79233.1,
CCDS26744.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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