| Type | Description |
|---|---|
| Definition | G protein-coupled receptor kinase 5 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 11:17:00 | Overexpression of GRK5-NT in cardiomyoblasts significantly reduced the activation and the nuclear translocation of NFAT and its cofactor GATA-4 in response to phenylephrine. | 29543709 |
| 2018-06-30 12:31:00 | This study showed that the GRK5 was involved in the development of epilepsy. It was associated with dendritic formation in epilepsy. | 29080472 |
| 2017-02-18 10:28:00 | results suggest that GRK5 may be involved in a UII-mediated hypertrophic response via activation of NF-kappaB and HDAC5 at least in part by ERK1/2 and GSK3alpha/beta-independent pathways. | 27613164 |
| 2016-09-17 10:13:00 | Suggest a common regulatory pattern for the beta(1)-AR/GRK5 which is independent of cellular type or pathology. | 26248277 |
| 2013-12-07 12:29:00 | GRK5 nuclear translocation downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process | 23472081 |
| Type | IDs |
|---|---|
| Synonymous | Gprk5 |
| Gene |
UniProtKB-ID:
GRK5_RAT,
Q66HL7_RAT
UniprotKB:
Q62833,
Q66HL7
UniParc:
UPI000042AE62,
UPI000012BADD
EMBL:
AABR07007127,
BC081792,
CH473986,
AABR07007129,
U34841,
AABR07007128
Ensembl:
ENSRNOG00000011439
KO:
rno:59075
|
| Nucleutide sequences |
EMBL-CDS:
AAC52536.1,
AAH81792.1,
EDL94586.1
Gene_ORFName:
rCG_57758
Ensembl_TRS:
ENSRNOT00000015687
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000015687
RefSeq:
XP_017445121.1,
XP_006231748.1,
XP_017445122.1,
NP_110456.2
|
| Others |
UniRef100:
UniRef100_Q62833,
UniRef100_Q66HL7
UniRef90:
UniRef90_Q62833,
UniRef90_Q66HL7
UniRef50:
UniRef50_P32298-2,
UniRef50_P34947
UniGene:
Rn.6500
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员