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5906 RAP1A

5906

RAP1A

RAP1A, member of RAS oncogene family

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAP1A, member of RAS oncogene family

研究结论

Date Results Publications
2021-02-20 13:32:00 Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics. 32452765
2020-10-31 13:15:00 MiR-501-3p functions as a tumor suppressor in non-small cell lung cancer by downregulating RAP1A. 31805277
2020-09-12 16:05:00 Long noncoding RNA CRNDE promotes proliferation, migration and invasion in prostate cancer through miR-101/Rap1A. 32182086
2020-08-01 14:21:00 cooperative binding of Rap1 to the talin F0 and F1 domains synergizes with membrane PIP2 binding to spatiotemporally position and activate talins to regulate integrin activity 31578239
2020-08-01 12:53:00 When amino acids are limited, the Rap1-GTPases confine lysosomes to the perinuclear region and reduce lysosome abundance, which suppresses mTORC1 signaling. 32184389

名称对应

Type IDs
Synonymous C21KG, G-22K, KREV-1, KREV1, RAP1, SMGP21
Gene
UniProtKB-ID: RAP1A_HUMAN, A8KAH9_HUMAN
UniprotKB: P62834, A8KAH9
UniParc: UPI0000001250
EMBL: CH471122, AK293044, BC014086, AB451360, X12533, AF493912, AL049557, AB451235, M22995
Ensembl: ENSG00000116473
KO: hsa:5906
Nucleutide sequences
EMBL-CDS: AAA36150.1, CAA31051.1, AAM12626.1, AAH14086.1, BAF85733.1, BAG70049.1, EAW56503.1, BAG70174.1
Gene_ORFName: hCG_1818872
Ensembl_TRS: ENST00000356415, ENST00000369709
Protein sequencees
Ensembl_PRO: ENSP00000348786, ENSP00000358723
RefSeq: NP_002875.1, NP_001278825.1, NP_001357146.1, NP_001357145.1, NP_001010935.1
Others
UniRef100: UniRef100_P62834
UniRef90: UniRef90_P62834
UniRef50: UniRef50_P62834
UniGene: Hs.190334
CCDS: CCDS840.1

全选

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