| Type | Description |
|---|---|
| Definition | polynucleotide kinase 3'- phosphatase |
| Date | Results | Publications |
|---|---|---|
| 2017-12-30 12:36:00 | Repair independent of the well documented XRCC1-PNKP interaction was studied. XRCC1 can mediate repair of strand breaks without PNKP binding. | 29100039 |
| 2017-06-03 11:06:00 | The work indicates that the phosphatase domain of Pnkp binds 3'-phosphorylated single-stranded DNAs in a manner that is highly dependent on the presence of the 3'-phosphate. | 28276686 |
| 2016-01-16 11:39:00 | Directed postnatal neural inactivation of PNKP affected specific subpopulations including oligodendrocytes, indicating a broad requirement for genome maintenance, both during and after neurogenesis. | 26290337 |
| 2011-12-31 10:39:00 | Structure of dsDNA bound to PNK 5'-kinase domain reveals DNA bending facilitating recognition of DNA ends in the context of single-strand/double-strand breaks, suggesting close functional cooperation in between the kinase/phosphatase active sites. | 22055185 |
| 2010-01-21 00:00:00 | analysis of the molecular architecture of polynucleotide kinase | 15749016 |
| Type | IDs |
|---|---|
| Synonymous | 1810009G08Rik, PNK |
| Gene |
UniProtKB-ID:
G5E8N7_MOUSE,
E9Q9A5_MOUSE
UniprotKB:
G5E8N7,
E9Q9A5
UniParc:
UPI00001F49A3,
UPI0000D8A990
EMBL:
AC158231
Ensembl:
ENSMUSG00000002963
KO:
mmu:59047
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000003044,
ENSMUST00000107876,
ENSMUST00000098478
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003044,
ENSMUSP00000103508,
ENSMUSP00000096078
RefSeq:
XP_011249187.1,
XP_036009201.1,
XP_006541103.2,
XP_030098705.1,
NP_001277693.1,
XP_006541104.1,
XP_030098707.1,
NP_067524.2,
XP_030098709.1,
XP_030098706.1,
XP_006541105.2,
XP_006541102.2,
NP_001277695.1,
XP_006541101.2,
NP_001277696.1,
XP_030098708.1,
XP_036009200.1,
XP_017177921.1
|
| Others |
UniRef100:
UniRef100_E9Q9A5,
UniRef100_G5E8N7
UniRef90:
UniRef90_Q9JLV6
UniRef50:
UniRef50_Q96T60-2
UniGene:
Mm.238254
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员