| Type | Description |
|---|---|
| Definition | mediator complex subunit 12 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-02 12:04:00 | Med12 is critically important in reproductive tract development, and Med12 loss of function does not cause tumorigenesis in reproductive tissues. | 29126187 |
| 2017-09-09 12:14:00 | Study provide evidence that Med12 regulates neural stem cell gene expression programs linked to adhesion and cell cycle progression but suppresses its adhesion by repressing the expression of cell adhesion molecules. | 27188461 |
| 2017-07-22 10:40:00 | alterations in MED12-dependent enhancer regulation may control both physiological and malignant hematopoiesis. | 27570068 |
| 2017-05-20 11:45:00 | The data reveal how the interplay between PRC1, ncRNA and Mediator complexes controls pluripotency and cellular differentiation. | 27096886 |
| 2016-07-30 10:26:00 | Med1 and Med12, two subunits of the mediator complex implicated in transcription initiation and long-range enhancer/promoter loop formation, are dynamically recruited to the IgH locus enhancers. | 26903242 |
| Type | IDs |
|---|---|
| Synonymous | 230kDa, Mopa, OPA-1, Tnrc11, Trap230 |
| Gene |
UniProtKB-ID:
MED12_MOUSE,
Q2NLB9_MOUSE
UniprotKB:
A2AGH6,
Q2NLB9
UniParc:
UPI00001CDE71,
UPI0000EE05AB,
UPI00002192C5,
UPI000067A483
EMBL:
AK220216,
BC057085,
BC057119,
AL683892,
BC110696,
AF071310
Ensembl:
ENSMUSG00000079487
KO:
mmu:59024
|
| Nucleutide sequences |
EMBL-CDS:
AAH57119.1,
AAH57085.1,
AAC83164.1,
BAD90141.1,
AAI10697.1
Ensembl_TRS:
ENSMUST00000087948,
ENSMUST00000087956
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000085260,
ENSMUSP00000085269
RefSeq:
NP_067496.2
|
| Others |
UniRef100:
UniRef100_Q2NLB9,
UniRef100_A2AGH6
UniRef90:
UniRef90_Q93074,
UniRef90_A2AGH6-3
UniRef50:
UniRef50_Q93074,
UniRef50_A2AGH6-3
UniGene:
Mm.20873,
Mm.490933
CCDS:
CCDS41078.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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