| Type | Description |
|---|---|
| Definition | PDZ domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 10:11:00 | PDZK1 is required for anti-atherogenic responses in macrophages including HDL dependent protection against apoptosis and macrophage mediated efferocytosis and limits the accumulation of apoptotic cells within atherosclerotic plaques protecting against necrotic core development. | 29853191 |
| 2019-05-18 10:46:00 | Pdzk1, which plays a critical role in cholesterol metabolism and carnitine transport, was found in sperm lipid metabolism. Western blotting and immunofluorescence analyses showed that Pdzk1 was expressed in the epididymis but not in the testis, and localized at the middle piece of the sperm tail. | 29405165 |
| 2019-03-02 12:44:00 | NHERF2 and NHERF3 have overlapping roles in NHE3 stimulation by LPA and inhibition by elevated Ca(2+) and cGMP. | 28882822 |
| 2018-07-07 10:13:00 | Dysfunction of intestinal OCTN1 in mouse model of chronic kidney disease (CKD) impaired the OCTN1-ergothioneine axis, an adaptive antioxidant system, and that decreased antioxidant ergothioneine levels may contribute to CKD progression in a PDZK1-dependent manner. | 28754554 |
| 2018-02-17 10:48:00 | These results suggest that the PDZ domain of PICK1 directly interacts with calcineurin B in osteoclast progenitor cells and promotes osteoclast differentiation through activation of calcineurin-NFAT signaling. | 29305867 |
| Type | IDs |
|---|---|
| Synonymous | 1700023D20Rik, 2610507N21Rik, 4921513F16Rik, AI267131, AI314638, AL022680, D3Ertd537e, NHERF-3, Pdzd1, mPDZK1, naPi-Cap1 |
| Gene |
UniProtKB-ID:
NHRF3_MOUSE,
A0A0R4J1V0_MOUSE
UniprotKB:
Q9JIL4,
A0A0R4J1V0
UniParc:
UPI0000026875,
UPI00000E80A2
EMBL:
AK014879,
AK006269,
AK029764,
AF474247,
AF220100,
AK012070,
BC013512,
AK029752,
AC127297
Ensembl:
ENSMUSG00000038298
KO:
mmu:59020
|
| Nucleutide sequences |
EMBL-CDS:
BAB28007.1,
AAL84634.1,
BAC26598.1,
BAB29600.1,
BAB24493.1,
AAF73863.1,
BAC26605.1,
AAH13512.1
Ensembl_TRS:
ENSMUST00000153256,
ENSMUST00000107069,
ENSMUST00000058865,
ENSMUST00000107070
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000058936,
ENSMUSP00000118846,
ENSMUSP00000102685,
ENSMUSP00000102684
RefSeq:
NP_001139473.1,
XP_017175164.1,
NP_067492.2,
XP_011238480.1,
NP_001342639.1
|
| Others |
UniRef100:
UniRef100_A0A0R4J1V0,
UniRef100_Q9JIL4
UniRef90:
UniRef90_Q9JIL4
UniRef50:
UniRef50_Q5T2W1
UniGene:
Mm.489677
CCDS:
CCDS17649.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员