| Type | Description |
|---|---|
| Definition | SH3 domain containing ring finger 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-09 12:55:00 | The pro-apoptotic JNK scaffold protein POSH mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia. | 29432529 |
| 2017-07-29 10:19:00 | this study shows that POSH is essential for the integration of cell-type-specific signals that regulate the differentiation, survival, and function of T cells | 27084103 |
| 2014-03-22 11:22:00 | identify plenty of SH3 (POSH) and JNK-interacting protein 1 (JIP-1) as a multiprotein scaffold network for TCR-mediated JNK1 activation in CD8(+) T cells. | 23963642 |
| 2013-03-02 10:50:00 | a mechanism by which POSH regulates the localization of activated Rac1 and F-actin assembly to control PCDLP formation and subsequent somal translocation of migratory neurons. | 22959435 |
| 2010-10-30 10:33:00 | An intracellular signaling pathway for process outgrowth inhibition by Nogo66 implicates the POSH complex as a therapeutic target to enhance axon outgrowth and plasticity in the injured central nervous system. | 20926658 |
| Type | IDs |
|---|---|
| Synonymous | 2200003J05Rik, Posh, R75531, Sh3md2 |
| Gene |
UniProtKB-ID:
SH3R1_MOUSE,
E9QQ33_MOUSE
UniprotKB:
Q69ZI1,
E9QQ33
UniParc:
UPI000173AA30,
UPI000019326F,
UPI00000E9FF8,
UPI000173AA2F,
UPI000173AA2E
EMBL:
AC134339,
AK148137,
AK088003,
AC117196,
AK045470,
BC060696,
AK173185,
BC060113,
AF030131
Ensembl:
ENSMUSG00000031642
KO:
mmu:59009
|
| Nucleutide sequences |
EMBL-CDS:
AAH60113.1,
AAC40070.1,
AAH60696.1,
BAC32385.1,
BAC40088.1,
BAE28367.1,
BAD32463.1
Ensembl_TRS:
ENSMUST00000034060
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034060
RefSeq:
XP_036010097.1,
XP_011240533.1,
NP_067481.2
|
| Others |
UniRef100:
UniRef100_Q69ZI1,
UniRef100_E9QQ33
UniRef90:
UniRef90_Q69ZI1
UniRef50:
UniRef50_Q69ZI1
UniGene:
Mm.27949
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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