| Type | Description |
|---|---|
| Definition | N-glycanase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:06:00 | N-Glycanase 1 Transcriptionally Regulates Aquaporins Independent of Its Enzymatic Activity. | 31875565 |
| 2019-09-07 11:24:00 | findings reveal novel functions of the NGLY1-NRF1 (Nfe2l1) pathway in mitochondrial homeostasis and inflammation and uncover an unexpected therapeutic strategy using pharmacological activators of NRF2 for treating mitochondrial and immune dysregulation. | 30135079 |
| 2017-06-03 11:28:00 | These observations strongly suggest that the Ngly1- or Ngly1/Engase-deficient mice could serve as a valuable animal model for studies related to the pathogenesis of the NGLY1-deficiency, and that cytoplasmic ENGase represents one of the potential therapeutic targets for this genetic disorder. | 28426790 |
| 2015-05-02 11:00:00 | study underscores the functional importance of Ngly1 in the ERAD process and provides a potential mechanism underlying the phenotypic consequences of a newly emerging genetic disorder caused by mutation of the human NGLY1 gene | 25605922 |
| 2010-01-21 00:00:00 | Data show that both the yeast PNG1 enzyme and its mammalian homolog display N-glycanase activity towards intact glycoproteins. | 12606569 |
| Type | IDs |
|---|---|
| Synonymous | 1110002C09Rik, PNGase, Png1 |
| Gene |
UniProtKB-ID:
NGLY1_MOUSE
UniprotKB:
Q9JI78
UniParc:
UPI0000021CFC
EMBL:
AY225417,
AK028248,
BC028961,
AK003279,
AF250927
Ensembl:
ENSMUSG00000021785
KO:
mmu:59007
|
| Nucleutide sequences |
EMBL-CDS:
AAH28961.1,
AAP03060.1,
BAC25839.1,
AAF74723.1,
BAB22686.1
Ensembl_TRS:
ENSMUST00000022310
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022310
RefSeq:
NP_001349362.1,
NP_067479.2,
NP_001349361.1
|
| Others |
UniRef100:
UniRef100_Q9JI78
UniRef90:
UniRef90_Q9JI78
UniRef50:
UniRef50_Q96IV0-5
UniGene:
Mm.258381
CCDS:
CCDS26832.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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