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5900 RALGDS

5900

RALGDS

ral guanine nucleotide dissociation stimulator

protein-coding

Homo sapiens

基因描述

Type Description
Definition ral guanine nucleotide dissociation stimulator

研究结论

Date Results Publications
2012-12-22 10:46:00 Investigated is the role that electrostatic field differences caused by the charge reversal mutation Rap1A K31E play in determining the binding specificity of RalGDS to Rap1A versus Ras. 22738401
2010-01-21 13:07:00 Studies provide models for Ras in association with Raf kinase, RalGDS and PI3Kalpha and PI3Kgamma. 19801192
2010-01-21 00:00:00 These data extend understanding of the functional roles of the Ral pathway and begin to identify signaling pathways relevant for organ-specific metastasis. 17709381
2010-01-21 00:00:00 Merlin can function as a tumor suppressor by inhibiting the RalGDS-mediated oncogenic signals. 16007223
2010-01-21 00:00:00 identified Ral-GDS as a beta-arrestin-binding protein by yeast two-hybrid screening and co-immunoprecipitation from human polymorphonuclear neutrophilic leukocytes 12105416

名称对应

Type IDs
Synonymous RGDS, RGF, RalGEF
Gene
UniProtKB-ID: GNDS_HUMAN, Q8N4Y1_HUMAN
UniprotKB: Q12967, Q8N4Y1
UniParc: UPI00003775F5, UPI00001927A0, UPI00017BE782, UPI00015E027C, UPI0002064E02, UPI0000073F77, UPI000012B8BC
EMBL: BC059362, BC033198, U14417, AK301470, AF027169, AF295775, AK127524, AB037729, AL162417, AF295773, AF295778, CH471090, AF295780
Ensembl: ENSG00000160271
KO: hsa:5900
Nucleutide sequences
EMBL-CDS: AAH59362.1, EAW88042.1, AAA52360.1, AAG10221.1, AAQ13414.1, BAC87018.1, EAW88040.1, AAG02122.1, BAA92546.1, AAG10225.1, BAH13489.1, AAH33198.1
Ensembl_TRS: ENST00000372062, ENST00000372047, ENST00000372050, ENST00000393160, ENST00000393157
Protein sequencees
Ensembl_PRO: ENSP00000361132, ENSP00000376867, ENSP00000376864, ENSP00000361120, ENSP00000361117
RefSeq: NP_001258705.1, NP_006257.1, NP_001258703.1, NP_001258704.1, NP_001035827.1
Others
UniRef100: UniRef100_Q12967, UniRef100_A0A2R8Y471
UniRef90: UniRef90_Q12967
UniRef50: UniRef50_Q12967
UniGene: Hs.106185
CCDS: CCDS65172.1, CCDS6959.1, CCDS65173.1, CCDS43897.1, CCDS65174.1

全选

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