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5899 RALB

5899

RALB

RAS like proto-oncogene B

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAS like proto-oncogene B

研究结论

Date Results Publications
2020-11-21 13:11:00 Localization of RalB signaling at endomembrane compartments and its modulation by autophagy. 31222145
2020-01-04 11:38:00 RalA and RalB both relocalize to mitochondria following depolarization in a process dependent on clathrin-mediated endocytosis. Furthermore, both genetic and pharmacologic inhibition of RalA and RalB leads to an increase in the activity of the atypical IkappaB kinase TBK1 both basally and in response to mitochondrial depolarization. 30995277
2019-03-02 11:31:00 RalB expression at protein level increases in a manner consistent with progression toward metastasis. 30320548
2018-02-24 10:16:00 our work provides new insight into the specific roles of Ras effector pathways in acute myeloid leukemia and has identified RALB signaling as a key survival pathway 27556501
2017-12-02 10:26:00 This study identifies a novel regulatory crosstalk between Ral and Arf6 that controls Ral function in cells. 27269287

名称对应

Type IDs
Gene
UniProtKB-ID: RALB_HUMAN, A0A024RAG3_HUMAN
UniprotKB: P11234, A0A024RAG3
UniParc: UPI000000124F, UPI00017A8390, UPI00001C0E8F
EMBL: AK303214, M35416, AK127675, X15015, AC012363, AK312453, BT006953, BC018163, AF493911, CH471103
Ensembl: ENSG00000144118
KO: hsa:5899
Nucleutide sequences
EMBL-CDS: EAW95242.1, BAG35360.1, BAG64302.1, AAP35599.1, AAY14800.1, BAC87080.1, EAW95240.1, AAM12625.1, AAH18163.1, CAA33119.1, AAA60250.1, EAW95241.1
Gene_ORFName: hCG_17321
Ensembl_TRS: ENST00000420510, ENST00000272519
Protein sequencees
Ensembl_PRO: ENSP00000272519, ENSP00000414224
RefSeq: XP_011509876.1, XP_005263785.1, NP_001356329.1, NP_002872.1
Others
UniRef100: UniRef100_P11234
UniRef90: UniRef90_P11234
UniRef50: UniRef50_P11234
UniGene: Hs.469820
CCDS: CCDS2131.1

全选

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研究热度

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