| Type | Description |
|---|---|
| Definition | interleukin 22 receptor subunit alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:51:00 | Overexpression of IL22RA1 enhanced HTFs migration and proliferation, while miR-760 and miR-215-3p mimics reversed these promotive biological roles induced by IL22RA1. In conclusion, NR_003923 and IL22RA1 might contribute to glaucoma progression and be a novel and potential biomarkers and therapeutic targets for glaucoma | 31391457 |
| 2020-02-08 10:54:00 | During influenza infection, IL22RA1 is induced in the lung. | 31416461 |
| 2019-12-14 10:48:00 | The IL22 gene promoter SNP rs2227473 G allele is a risk factor for intestinal tuberculosis. High IL-22 expression seems to be a protective factor for intestinal tuberculosis. IL-22R1 is not only highly expressed in epithelial cells but also, unexpectedly, expressed in Langhans giant cells, contradicting the previous view that IL-22R1 is expressed only in non-haematopoietic cells. | 31171891 |
| 2019-08-03 10:18:00 | Study shows that high expression of IL22RA1 is associated with poor prognosis in pancreatic cancer. IL22 promotes pancreatic cancer stemness via signaling, identifying the mechanism of regulation of cancer stem cells by microenvironmental factors. Moreover, activation is indispensable for the maintenance of IL22RA1-hi cells, both in the absence or presence of IL22. | 29572224 |
| 2019-03-02 12:03:00 | found obvious statistic difference for the allele of early-onset PE/the genotype of late-onset preeclampsia (PE) and control subgroups for IL-22 rs2227485. IL-22 rs2227485 and IL-22RA1 rs3795299 may be associated with the development of PE in Chinese Han population. | 29274280 |
| Type | IDs |
|---|---|
| Synonymous | CRF2-9, IL22R, IL22R1 |
| Gene |
UniProtKB-ID:
I22R1_HUMAN
UniprotKB:
Q8N6P7
UniParc:
UPI0000071143
EMBL:
BC029273,
AK313971,
AF286095,
AL590683,
AK292204,
AL591178,
CH471134
Ensembl:
ENSG00000142677
KO:
hsa:58985
|
| Nucleutide sequences |
EMBL-CDS:
AAH29273.1,
EAW95111.1,
BAG36686.1,
BAF84893.1,
AAG22073.1
Ensembl_TRS:
ENST00000270800
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000270800
RefSeq:
NP_067081.2,
XP_011540184.1
|
| Others |
UniRef100:
UniRef100_Q8N6P7
UniRef90:
UniRef90_Q8N6P7
UniRef50:
UniRef50_Q8N6P7
UniGene:
Hs.110915
CCDS:
CCDS247.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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