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58968 Acan

58968

Acan

aggrecan

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition aggrecan

研究结论

Date Results Publications
2019-06-22 10:17:00 E1 and E2 enhancer activities in type II collagen and aggrecan are regulated through distinct epigenetic modifications by histone deacetylase 10 and sirtuin 6. 30981839
2016-06-28 10:27:00 The ERK1/2 and Smad2/3 signaling pathways regulate type II collagen and aggrecan expression in rat chondrocytes. 26165845
2015-04-04 11:27:00 To elucidate the transcriptional mechanism that leads to abundant expression of aggrecan by chondrocytes, it screened for enhancer elements in 130 kb of the aggrecan gene, Agc1, using a reporter assay system that we previously developed. 24554731
2015-02-28 13:27:00 Local adipose tissue stem cells protected the bronchial stump after pneumonectomy and induced local changes in Agc1 gene expression. 24647564
2013-06-08 12:58:00 These results support a role for MafB as a regulator of chondrocyte gene expression and matrix formation via control of aggrecan, MMP3 and MMP13 expression, and indicate an important role for RA in the regulation of MafB 22961837

名称对应

Type IDs
Synonymous Agc, Agc1
Gene
UniProtKB-ID: PGCA_RAT
UniprotKB: P07897
UniParc: UPI0001D14772, UPI0000131783
EMBL: M13518, J03485
KO: rno:58968
Nucleutide sequences
EMBL-CDS: AAA21000.1, AAA41836.1
Protein sequencees
RefSeq: NP_071526.1
Others
UniRef100: UniRef100_P07897
UniRef90: UniRef90_P07897
UniRef50: UniRef50_P16112
UniGene: Rn.54503

全选

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研究热度

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