| Type | Description |
|---|---|
| Definition | family with sequence similarity 13, member A |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:30:00 | Loss of Family with Sequence Similarity 13, Member A Exacerbates Pulmonary Fibrosis Potentially by Promoting Epithelial to Mesenchymal Transition. | 32029695 |
| 2020-07-18 10:25:00 | GWAS-associated variants within the FAM13A locus alter adipose FAM13A expression, which in turn, regulates adipocyte differentiation and contribute to changes in body fat distribution. | 32193374 |
| 2020-05-16 10:23:00 | Fam13a expression was reduced in the lungs of mice with hypoxia-induced pulmonary hypertension. Genetic loss of Fam13a exacerbated pulmonary hypertension in mice exposed to chronic hypoxia in association with deteriorated pulmonary artery remodeling. Study data revealed a protective role of Fam13a in the development of pulmonary hypertension. | 32053709 |
| 2020-04-25 12:44:00 | Fam13a(-/-) mice only exhibited a tendency of higher adiposity and were not protected from DIO and insulin resistance. While Fam13a(-/-) SVCs maintained normal adipogenesis, overexpression of FAM13A in 3T3-L1 preadipocytes downregulated beta-catenin signaling and rendered preadipocytes more susceptible to apoptosis | 30301961 |
| 2018-07-28 11:23:00 | Genetic loss of Fam13a exacerbated obesity-related metabolic disorders. | 29386390 |
| Type | IDs |
|---|---|
| Synonymous | AI462012, D430015B01Rik, FAM13A1, Precm1 |
| Gene |
UniProtKB-ID:
FA13A_MOUSE
UniprotKB:
Q8BGI4
UniParc:
UPI000002788A
EMBL:
AK036291,
BC080861,
AK052421,
AJ510136
Ensembl:
ENSMUSG00000037709
KO:
mmu:58909
|
| Nucleutide sequences |
EMBL-CDS:
BAC29374.1,
CAD52865.1,
AAH80861.1,
BAC34983.1
Ensembl_TRS:
ENSMUST00000089860
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000087304
RefSeq:
NP_705802.1
|
| Others |
UniRef100:
UniRef100_Q8BGI4
UniRef90:
UniRef90_Q8BGI4
UniRef50:
UniRef50_O94988-1
UniGene:
Mm.28813
CCDS:
CCDS39499.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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