| Type | Description |
|---|---|
| Definition | RAD23 homolog B, nucleotide excision repair protein |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:08:00 | Histone H4K20 Demethylation by Two hHR23 Proteins. | 32209475 |
| 2021-03-20 13:33:00 | Functional impacts of the ubiquitin-proteasome system on DNA damage recognition in global genome nucleotide excision repair. | 33184426 |
| 2021-01-23 12:57:00 | Inhibition of Excision of Oxidatively Generated Hydantoin DNA Lesions by NEIL1 by the Competitive Binding of the Nucleotide Factor XPC-RAD23B. | 32302101 |
| 2020-06-20 12:10:00 | Study reports RAD23B copy number variation in 10% (12/119, P a collection or group of signs and symptoms that occur together and characterize a particular disease or abnormality." data-original-title="Syndrome" data-html="true" data-trigger="foucs">syndrome (SS) patients, associated with reduced mRNA expression. RAD23B knockdown in a cutaneous T-cell lymphoma cell line led to a reduction in FK228-induced apoptosis. Findings suggest that RAD23B gene perturbations could reduce sensitivity to histone deacetylase inhibitors in SS patients. | 30910759 |
| 2020-01-11 10:50:00 | TYMS was absent in 100% of circulating tumor cells (CTCs) from locally advanced rectal cancer patients with pathologic complete response yet was expressed in 83% of non-responders prior to surgery (S2). RAD23B was expressed in CTCs from 75% of non-responders prior to neoadjuvant chemoradiation (S1) and in 100% of non-responders at S2. 100% of non-responders expressed TYMS mRNA at both timepoints. | 31247977 |
| Type | IDs |
|---|---|
| Synonymous | HHR23B, HR23B, P58 |
| Gene |
UniProtKB-ID:
RD23B_HUMAN,
B7Z4W4_HUMAN
UniprotKB:
P54727,
B7Z4W4
UniParc:
UPI0000EE5FDF,
UPI000022D96E,
UPI0000132F6C
EMBL:
AL137852,
AK125226,
AK297986,
BC020973,
AY313777,
AY165178,
D21090,
CH471105
Ensembl:
ENSG00000119318
KO:
hsa:5887
|
| Nucleutide sequences |
EMBL-CDS:
EAW59017.1,
AAP81008.1,
BAA04652.1,
EAW59016.1,
AAH20973.1,
BAG54170.1,
AAN47194.1,
BAH12700.1
Ensembl_TRS:
ENST00000416373,
ENST00000358015
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000405623,
ENSP00000350708
RefSeq:
NP_001231642.1,
NP_002865.1,
NP_001231653.1
|
| Others |
UniRef100:
UniRef100_P54727,
UniRef100_B7Z4W4
UniRef90:
UniRef90_G3T069,
UniRef90_P54727
UniRef50:
UniRef50_P54727,
UniRef50_M3X1H1
UniGene:
Hs.521640
CCDS:
CCDS6769.1,
CCDS59138.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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