| Type | Description |
|---|---|
| Definition | L-threonine dehydrogenase |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 12:00:00 | TDH, responsible for mitochondrial production of acetyl-CoA in mouse embryonic stem cells, and the acetyltransferase GCN5L1 cooperate to acetylate Lys501 in KBP, allowing its recognition by and degradation via Fbxo15, an F-box protein transcriptionally controlled by the pluripotency core factors and repressed following differentiation. | 28319092 |
| 2011-12-17 11:40:00 | Data shsow that metabolic flux through the TDH pathway is required for the viability and self-renewal of ES cells. | 21896756 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TDH_MOUSE
UniprotKB:
Q8K3F7
UniParc:
UPI0000021D7F
EMBL:
AY116662,
AF134346,
BC058860,
AK077571
Ensembl:
ENSMUSG00000021953
KO:
mmu:58865
|
| Nucleutide sequences |
EMBL-CDS:
BAC36870.1,
AAF61395.2,
AAM51557.1,
AAH58860.1
Ensembl_TRS:
ENSMUST00000022522
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022522
RefSeq:
NP_067455.5
|
| Others |
UniRef100:
UniRef100_Q8K3F7
UniRef90:
UniRef90_Q8K3F7
UniRef50:
UniRef50_Q8K3F7
UniGene:
Mm.354229
CCDS:
CCDS27202.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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