| Type | Description |
|---|---|
| Definition | nuclear receptor subfamily 1, group H, member 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-08 10:54:00 | We observed increased expression of LXRalpha from an early stage of nephrosis. To explore the role of increased LXRalpha in diseased kidney in vitro, NRK52E, normal kidney tubular epithelial cells, were forced to overexpress LXRalpha. These cells showed significantly lower lipid accumulation than mock cells did. In contrast, LXRbeta knockdown led to increased lipid accumulation in mock cells, and constancy in overexpre... | 30471864 |
| 2018-07-21 10:48:00 | the results of the present study suggested that diosgenin is a potential agent for preventing the development of NAFLD through the AMPK and LXR signaling pathways. | 29207101 |
| 2017-12-02 10:44:00 | The present study indicates a requirement for C/EBPbeta in the insulin-mediated induction of SREBP-1c mRNA expression in rodent liver. Coupled with previous data showing that this induction requires LXRalpha, our data reported herein indicate a requirement for both transcription factors. | 27382175 |
| 2017-02-18 10:18:00 | Data show that TO901317 increased expression of both Liver X receptors (LXRalpha and LXRbeta) isoforms and its target genes: sterol response element binding protein 1c (SREBP-1c) and acetyl-coenzyme A carboxylase 1 (ACC1) in the heart of streptozotocin-diabetes. | 27352290 |
| 2016-07-16 10:47:00 | treatment significantly downregulated LXRalpha expression and improve steatotic liver graft function and recipient survival after a fatty liver transplantation in rats. | 26256083 |
| Type | IDs |
|---|---|
| Synonymous | LXRalpha |
| Gene |
UniProtKB-ID:
Q5I035_RAT
UniprotKB:
Q5I035
UniParc:
UPI000019BDC5
EMBL:
BC088750,
CH473949,
AABR07052865
Ensembl:
ENSRNOG00000013172
KO:
rno:58852
|
| Nucleutide sequences |
EMBL-CDS:
EDL79513.1,
AAH88750.1,
EDL79514.1
Gene_ORFName:
rCG_27182
Ensembl_TRS:
ENSRNOT00000018154
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000018154
RefSeq:
XP_006234597.1,
NP_113815.2,
XP_006234599.1,
XP_006234596.1,
XP_006234595.1
|
| Others |
UniRef100:
UniRef100_Q5I035
UniRef90:
UniRef90_Q9Z0Y9
UniRef50:
UniRef50_Q13133
UniGene:
Rn.11209
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员