| Type | Description |
|---|---|
| Definition | SH2B adaptor protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:59:00 | MicroRNA-29b upregulation improves myocardial fibrosis and cardiac function in myocardial infarction rats through targeting SH2B3. | 31799683 |
| 2016-01-30 10:45:00 | These data demonstrate for the first time that SH2B3 is a crucial mediator of post-MI inflammation and fibrosis. | 25628389 |
| 2015-11-07 11:36:00 | SH2B3 functions as a novel and effective modulator of cardiac remodeling and failure. | 26101343 |
| 2015-06-20 12:10:00 | The resulting mutation was a 6-bp, in-frame deletion within a highly conserved region of the Src homology 2 (SH2) domain of SH2B3. This mutation significantly attenuated Dahl SS hypertension and renal disease. | 25776069 |
| 2012-02-25 10:58:00 | SH2B3 inhibits neuronal differentiation of PC12 cells and primary cortical neurons | 22028877 |
| Type | IDs |
|---|---|
| Synonymous | Lnk |
| Gene |
UniProtKB-ID:
SH2B3_RAT
UniprotKB:
P50745
UniParc:
UPI000012E799,
UPI000002AD5E,
UPI000002AD5C,
UPI000002AD5D
EMBL:
U24655,
U24652,
U24653,
U24654
KO:
rno:58838
|
| Nucleutide sequences |
EMBL-CDS:
AAC52349.1,
AAC52348.1,
AAC52351.1,
AAC52350.1
|
| Protein sequencees |
RefSeq:
NP_113809.1
|
| Others |
UniRef100:
UniRef100_P50745
UniRef90:
UniRef90_P50745
UniRef50:
UniRef50_P50745
UniGene:
Rn.11228
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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