| Type | Description |
|---|---|
| Definition | RAD9 checkpoint clamp component A |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:49:00 | Rad9/53BP1 promotes DNA repair via crossover recombination by limiting the Sgs1 and Mph1 helicases. | 32576832 |
| 2020-03-21 10:35:00 | breast and lung tumor suppressive activities of resveratrol are, at least in part, mediated by the upregulation of Rad9 in a DNA damage response pathway involving reactive oxygen species | 31310624 |
| 2019-11-09 10:16:00 | RAD9A drives metastasis by controlling AGR2 abundance. | 30295739 |
| 2018-07-14 11:54:00 | The authors show that human Cyclin-Dependent-Kinases (CDKs) target the RAD9 subunit of the 9-1-1 checkpoint clamp on Thr292, to modulate DNA damage checkpoint activation. Thr292 phosphorylation on RAD9 creates a binding site for Polo-Like-Kinase1 (PLK1), which phosphorylates RAD9 on Thr313. | 29254517 |
| 2016-10-22 11:56:00 | TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint | 26860083 |
| Type | IDs |
|---|---|
| Synonymous | RAD9 |
| Gene |
UniProtKB-ID:
RAD9A_HUMAN
UniprotKB:
Q99638
UniParc:
UPI000006D789
EMBL:
BC014848,
U53174,
AY766122,
CR536508,
AK315348,
CH471076
Ensembl:
ENSG00000172613
KO:
hsa:5883
|
| Nucleutide sequences |
EMBL-CDS:
EAW74605.1,
AAB39928.1,
AAH14848.1,
BAG37745.1,
CAG38746.1,
AAU89725.1
Ensembl_TRS:
ENST00000307980
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000311360
RefSeq:
XP_016873586.1,
NP_001230153.1,
XP_006718715.1,
NP_004575.1,
XP_016873587.1
|
| Others |
UniRef100:
UniRef100_Q99638
UniRef90:
UniRef90_Q99638
UniRef50:
UniRef50_Q99638
UniGene:
Hs.655354
CCDS:
CCDS8159.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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