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58819 Txnrd1

58819

Txnrd1

thioredoxin reductase 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition thioredoxin reductase 1

研究结论

Date Results Publications
2021-03-13 13:17:00 Compensatory Neuroprotective Response of Thioredoxin Reductase against Oxidative-Nitrosative Stress Induced by Experimental Autoimmune Encephalomyelitis in Rats: Modulation by Theta Burst Stimulation. 32867364
2017-09-30 10:33:00 Data suggest TrxR1 and NADPH directly protect PTP1B from inactivation by oxidation; this protection is independent of TRX1 and PRX2; this protection is blocked by auranofin (an inhibitor of TrxR1 and requires an intact selenocysteine residue in TrxR1. (TrxR1 = thioredoxin reductase 1; PTP1B = protein tyrosine phosphatase, non-receptor type 1; TRX1 = thioredoxin-1; PRX2 = paired related homeobox 2 protein) 28684416
2017-08-05 10:32:00 Inhibition of thioredoxin reductase-1 by brevetoxin-2 is via the formation of a Michael adduct between selenocysteine and the alpha, beta-unsaturated aldehyde moiety of the toxin. 28551108
2015-11-07 10:27:00 rat liver selenoenzyme thioredoxin reductase (Txnrd1, TR1) efficiently reduces tetrathionate 26252619
2015-10-17 11:33:00 DSW drinking reduced ulcer area as well as apoptotic signaling in acetic acid-induced duodenal ulcers. DSW, which contains selenium, provides intestinal protection against duodenal ulcers through the upregulation of Bcl-2 and thioredoxin reductase 24984066

名称对应

Type IDs
Synonymous Tr
Gene
Nucleutide sequences
Protein sequencees
RefSeq: NP_001338912.1, NP_001338913.1, NP_113802.2, NP_001338910.1
Others
UniGene: Rn.67581

全选

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