RAC3 - Rac family small GTPase 3-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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5881 RAC3

基因描述

Type	Description
Definition	Rac family small GTPase 3

研究结论

Date	Results	Publications
2021-03-20 13:35:00	Rac Family Small GTPase 3 Correlates with Progression and Poor Prognosis in Bladder Cancer.	33600260
2020-02-08 10:54:00	Our study supports that RAC3 variants cause syndromic neurodevelopmental disorders and brain structural abnormality, and expands the phenotypic spectrum of RAC3-related disorders.	31420595
2019-06-22 10:31:00	Missense variants in RAC3 cause a novel brain disorder, likely through a mechanism of constitutive protein activation	30293988
2017-12-09 11:15:00	Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation.	29061650
2017-02-18 10:23:00	Rac3 regulates the biological behaviors of lung adenocarcinoma through a mechanism of downregulating CCND1, MYC, and TFDP1 of cell cycle pathway.	27402308

名称对应

Type	IDs
Gene	UniProtKB-ID: RAC3_HUMAN UniprotKB: P60763 UniParc: UPI00000041DA EMBL: BC009605, BC015197, BT019443, AF498966, AF008591 Ensembl: ENSG00000169750 KO: hsa:5881
Nucleutide sequences	EMBL-CDS: AAC51667.1, AAH09605.1, AAV38250.1, AAM21113.1, AAH15197.1 Ensembl_TRS: ENST00000306897
Protein sequencees	Ensembl_PRO: ENSP00000304283 RefSeq: NP_005043.1, NP_001303236.1
Others	UniRef100: UniRef100_P60763 UniRef90: UniRef90_P60763 UniRef50: UniRef50_P60763 UniGene: Hs.45002 CCDS: CCDS11798.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
33600260	Rac Family Small GTPase 3 Correlates with Progression and Poor Prognosis in Bladder Cancer. DNA Cell Biol Wenjie Zheng , Jie Zhang , Qianqian Song , Yuqing Xu , Mengqi Zhu , Jianguo Ma	2021-03-01	-
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
32203420	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions. Nat. Cell Biol. Paul M MÃ¼ller , Juliane Rademacher , Richard D Bagshaw , Celina Wortmann , Carolin Barth , Jakobus van Unen , Keziban M Alp , Girolamo Giudice , Rebecca L Eccles , Louise E Heinrich , Patricia Pascual-Vargas , Marta Sanchez-Castro , Lennart Brandenburg , Geraldine Mbamalu , Monika Tucholska , Lisa Spatt , Maciej T Czajkowski , Robert-William Welke , Sunqu Zhang , Vivian Nguyen , Trendelina Rrustemi , Philipp Trnka , Kiara Freitag , Brett Larsen , Oliver Popp , Philipp Mertins , Anne-Claude Gingras , Frederick P Roth , Karen Colwill , Chris Bakal , Olivier Pertz , Tony Pawson , Evangelia Petsalaki , Oliver Rocks	2020-04-01	-
31420595	A de novo variant in RAC3 causes severe global developmental delay and a middle interhemispheric variant of holoprosencephaly. J Hum Genet Takuya Hiraide , Hikari Kaba Yasui , Mitsuhiro Kato , Mitsuko Nakashima , Hirotomo Saitsu	2019-11-01	-
31091453	PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. Cell Rep Adnan Shami Shah , Alex G Batrouni , Dongsung Kim , Amith Punyala , Wendy Cao , Chun Han , Michael L Goldberg , Marcus B Smolka , Jeremy M Baskin	2019-05-14	-
30293988	De novo missense variants in RAC3 cause a novel neurodevelopmental syndrome. Genet. Med. Gregory Costain , Bert Callewaert , Heinz Gabriel , Tiong Y Tan , Susan Walker , John Christodoulou , Tamas Lazar , BjÃ¶rn Menten , Julia Orkin , Simon Sadedin , Meaghan Snell , Arnaud Vanlander , Sarah Vergult , Susan M White , Stephen W Scherer , Robin Z Hayeems , Susan Blaser , Shoshana J Wodak , David Chitayat , Christian R Marshall , M Stephen Meyn	2019-04-01	-
29276006	WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome. Am J Hum Genet Janson J White , Juliana F Mazzeu , Zeynep Coban-Akdemir , Yavuz Bayram , Vahid Bahrambeigi , Alexander Hoischen , Bregje W M van Bon , Alper Gezdirici , Elif Yilmaz Gulec , Francis Ramond , Renaud Touraine , Julien Thevenon , Marwan Shinawi , Erin Beaver , Jennifer Heeley , Julie Hoover-Fong , Ceren D Durmaz , Halil Gurhan Karabulut , Ebru Marzioglu-Ozdemir , Atilla Cayir , Mehmet B Duz , Mehmet Seven , Susan Price , Barbara Merfort Ferreira , Angela M Vianna-Morgante , Sian Ellard , Andrew Parrish , Karen Stals , Josue Flores-Daboub , Shalini N Jhangiani , Richard A Gibbs , Baylor-Hopkins Center for Mendelian Genomics , Han G Brunner , V Reid Sutton , James R Lupski , Claudia M B Carvalho	2018-01-04	-
29061650	Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol Sara K Donnelly , Ramon Cabrera , Serena P H Mao , John R Christin , Bin Wu , Wenjun Guo , Jose Javier Bravo-Cordero , John S Condeelis , Jeffrey E Segall , Louis Hodgson	2017-12-04	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
27432908	Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Mol Cell Proteomics Xu Li , Kim My Tran , Kathryn E Aziz , Alexey V Sorokin , Junjie Chen , Wenqi Wang	2016-09-01	-

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