| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase kinase kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-01 10:45:00 | MAP4K2 was up-regulated and its expression was inversely correlated with collagen expression in the osteoblasts from older donors. | 30217450 |
| 2017-08-05 10:11:00 | These studies demonstrate, for the first time, that GCK is a molecular therapeutic target in DLBCL tumors and that inhibiting GCK may significantly extend DLBCL patient survival. | 27151888 |
| 2015-05-02 11:52:00 | Data indicate 4-substituted 1H-pyrrolo[2,3-b]pyridines as potent inhibitors against TGFbeta-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). | 25075558 |
| 2014-01-25 11:55:00 | Intermediates in the guanine nucleotide exchange reaction of Rab8 protein catalyzed by guanine nucleotide exchange factors Rabin8 and GRAB. | 24072714 |
| 2012-08-04 11:42:00 | Data suggest that the Rabin8-Rab8-Sec15 interaction may couple the activation of Rab8 to the recruitment of the Rab8 effector and is involved in the regulation of vesicular trafficking for primary cilium formation. | 22433857 |
| Type | IDs |
|---|---|
| Synonymous | BL44, GCK, RAB8IP |
| Gene |
UniProtKB-ID:
M4K2_HUMAN,
A0A024R567_HUMAN
UniprotKB:
Q12851,
A0A024R567
UniParc:
UPI000013E13D,
UPI000000DC63
EMBL:
AP001462,
U07349,
BC047865,
CH471076
Ensembl:
ENSG00000168067
KO:
hsa:5871
|
| Nucleutide sequences |
EMBL-CDS:
EAW74302.1,
AAA20968.1,
AAH47865.1,
EAW74299.1,
EAW74301.1
Gene_ORFName:
hCG_23379
Ensembl_TRS:
ENST00000377350,
ENST00000294066
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000294066,
ENSP00000366567
RefSeq:
XP_016873584.1,
XP_024304398.1,
XP_024304399.1,
XP_024304397.1,
XP_024304401.1,
NP_004570.2,
NP_001294919.1,
XP_011543506.1,
XP_024304402.1,
XP_016873582.1
|
| Others |
UniRef100:
UniRef100_Q12851
UniRef90:
UniRef90_Q12851
UniRef50:
UniRef50_Q12851
UniGene:
Hs.534341
CCDS:
CCDS81582.1,
CCDS8082.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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