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587 BCAT2

587

BCAT2

branched chain amino acid transaminase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition branched chain amino acid transaminase 2

研究结论

Date Results Publications
2020-06-13 10:32:00 The crystal structure of the oxidized form of the C318A variant of the human mitochondrial branched-chain aminotransferase was used to better understand the contributions of the individual cysteines and their oxidation states. 31929181
2020-04-18 12:36:00 BCAT2-mediated branched-chain amino acids catabolism is critical for the development of pancreatic ductal adenocarcinoma-harboring KRAS mutations. 32029896
2019-02-02 12:01:00 Skeletal muscle amino acid transporter and BCAT2 expression prior to and following interval running or resistance exercise in mode-specific trained males. 29725856
2018-07-21 10:33:00 Data suggest that both oncogenic mutations and cancer tissue-of-origin influence BCAA (branched-chain amino acid) metabolism in neoplastic tissue and neoplastic expression of cytosolic BCAT1 and mitochondrial BCAT2. (BCAT = branched-chain-amino-acid transaminase) [REVIEW] 29211698
2013-02-16 12:06:00 The mitochondrial isoform human brain BCAT 2 is largely confined to vascular endothelial cells, whereas the cytosolic human brain BCAT 1 is restricted to neurons. 23043456

名称对应

Type IDs
Synonymous BCAM, BCATM, BCT2, PP18
Gene
UniProtKB-ID: BCAT2_HUMAN, B3KSI3_HUMAN
UniprotKB: O15382, B3KSI3
UniParc: UPI000002A4C0, UPI00001267CC, UPI0000072AE3
EMBL: AF268047, U62739, CH471177, BC004243, AF268048, AK093627, U68418, AK314548, AC026803, BC001900
Ensembl: ENSG00000105552
KO: hsa:587
Nucleutide sequences
EMBL-CDS: AAK38368.1, AAH04243.2, AAK38369.1, AAB67672.1, AAB53087.1, EAW52403.1, BAG37134.1, AAH01900.1, BAG52745.1
Ensembl_TRS: ENST00000545387, ENST00000316273, ENST00000597011, ENST00000402551
Protein sequencees
Ensembl_PRO: ENSP00000440973, ENSP00000322991, ENSP00000469651, ENSP00000385161
RefSeq: NP_001181.2, NP_001158245.1, NP_001271254.1, XP_024307398.1
Others
UniRef100: UniRef100_O15382
UniRef90: UniRef90_O15382
UniRef50: UniRef50_O15382
UniGene: Hs.512670
CCDS: CCDS12735.1, CCDS54290.1

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