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5869 RAB5B

5869

RAB5B

RAB5B, member RAS oncogene family

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAB5B, member RAS oncogene family

研究结论

Date Results Publications
2020-07-11 10:41:00 The single nucleotide polymorphisms of the rs1045435, rs11550558, rs705700, and rs11171718 loci of the RAB5B gene are associated with polycystic ovary syndrome risk. The rs1045435 locus is likely an miR-24 binding site, while rs11550558, rs705700, and rs11171718 loci may be miR-320 binding sites. 31036605
2020-06-06 13:13:00 Therefore, it was considered that Rab5B is required for the transport of large hepatitis B virus surface proteins from the endoplasmic reticulum to multivesicular body. 31118260
2018-10-27 10:42:00 Knockdown of RAB5B inhibited cell proliferation, migration and invasion in breast cancer stem cell-like cells. MiR-130a-3p inhibits migration and invasion by regulating RAB5B in human breast cancer stem cell-like cells. 29746865
2016-03-19 10:09:00 results suggest that LRRK2 kinase activity functions as a Rab5b GTPase activating protein and thus, negatively regulates Rab5b signalling 25605758
2014-04-19 12:13:00 combined genetic association studies in women from China/Netherlands/United States: Data suggest that an SNP in RAB5B locus (rs705702) and SNPs in other proteins are associated with polycystic ovary syndrome across ethnic differences. [META-ANALYSIS] 24106282

名称对应

Type IDs
Gene
UniProtKB-ID: RAB5B_HUMAN, A0A024RB09_HUMAN
UniprotKB: P61020, A0A024RB09
UniParc: UPI0000EE2715, UPI000000125D
EMBL: BX537408, X54871, AF498937, AK292597, AC034102, BC065298, BC056422, BC050558, BC040143, CH471054, AK296517, BC032740
Ensembl: ENSG00000111540
KO: hsa:5869
Nucleutide sequences
EMBL-CDS: AAH56422.2, AAH32740.1, CAA38653.1, BAG59149.1, AAH40143.1, EAW96862.1, AAM21085.1, AAH65298.2, EAW96864.1, AAH50558.2, BAF85286.1, CAD97650.1, EAW96863.1
Gene_ORFName: hCG_25009
Ensembl_TRS: ENST00000360299, ENST00000553116, ENST00000448789
Protein sequencees
Ensembl_PRO: ENSP00000391319, ENSP00000353444, ENSP00000450168
RefSeq: XP_005269108.1, NP_001238966.1, NP_002859.1, NP_001238965.1, XP_005269109.1
Others
UniRef100: UniRef100_P61020
UniRef90: UniRef90_P61020
UniRef50: UniRef50_P20339
UniGene: Hs.157659
CCDS: CCDS58244.1, CCDS8900.1

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