| Type | Description |
|---|---|
| Definition | quinoid dihydropteridine reductase |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 11:30:00 | show for the first time statistically significant up regulation of iNOS in QDPR overexpressing astrocytes. Increased expression of iNOS associated with astrocyte pathology seen in many neurodegenerative disorders may have implications in autoimmune neurodegenerative disorders. | 29355631 |
| 2018-05-05 11:56:00 | Mutation of dihydropteridine reductase (QDPR) inhibited the regulation of TOR serine-threonine kinases (mTOR), suggesting that QDPR is a positive regulator of autophagy via suppressing mTOR signaling. | 28633336 |
| 2017-05-20 15:04:00 | The allele frequencies for the QDPR c.68G > A(0.3%) polymorphism is not a major cause of Parkinson's disease in the Maltese. | 27613114 |
| 2015-06-06 11:48:00 | The mutation spectrum of the QDPR gene is different in the Chinese population. Most mutations are related to severe phenotype. | 25124972 |
| 2012-02-25 11:15:00 | JP1 and JP2 can facilitate the assembly of DHPR with other proteins of the excitation-contraction coupling machinery | 22020936 |
| Type | IDs |
|---|---|
| Synonymous | DHPR, HDHPR, PKU2, SDR33C1 |
| Gene |
UniProtKB-ID:
DHPR_HUMAN,
A0A140VKA9_HUMAN
UniprotKB:
P09417,
A0A140VKA9
UniParc:
UPI0000111B0A,
UPI00004A22CB
EMBL:
AJ006245,
CH471069,
AK124382,
BC000576,
AC093600,
AJ006240,
X04882,
AJ006241,
AK223437,
HM005649,
AJ006244,
AJ006239,
AJ006242,
AB053170,
M16447,
AK289773,
AJ006243
Ensembl:
ENSG00000151552
KO:
hsa:5860
|
| Nucleutide sequences |
EMBL-CDS:
EAW92777.1,
BAB20429.1,
CAA28571.1,
AAA52305.1,
BAF82462.1,
BAD97157.1,
BAG54033.1,
AAH00576.1,
EAW92778.1,
CAA06930.1,
AEE61246.1
Ensembl_TRS:
ENST00000428702,
ENST00000281243
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000390944,
ENSP00000281243
RefSeq:
NP_001293069.1,
NP_000311.2
|
| Others |
UniRef100:
UniRef100_P09417
UniRef90:
UniRef90_P09417
UniRef50:
UniRef50_P09417
UniGene:
Hs.75438
CCDS:
CCDS77904.1,
CCDS3421.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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