| Type | Description |
|---|---|
| Definition | glutaminyl-tRNA synthetase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:29:00 | [QARS1 gene related glutaminyl-tRNA synthetase deficiency syndrome: report of three cases and a review of literature]. | 33256324 |
| 2018-04-28 11:22:00 | patient's fibroblasts demonstrated markedly reduced QARS amino acylation activity in vitro | 28620870 |
| 2017-03-25 11:57:00 | hcmv-miR-US4-1 may involve in promoting cell apoptosis and benefiting discharge of infectious virus particles via down-regulation of QARS in HCMV-infected HELF cells. | 27240979 |
| 2016-09-24 10:05:00 | Pathological mutations mapping in the N-terminal domain alter the domain structure, and decrease catalytic activity and stability of GlnRS, whereas missense mutations in the catalytic domain induce misfolding of the enzyme. | 26869582 |
| 2016-04-02 11:25:00 | Data indicate compound heterozygous mutations [c.169T>C (p.Tyr57His) and c.1485dup (p.Lys496*)] in QARS, which encodes glutaminyl-tRNA synthetase, in two siblings with early-onset epileptic encephalopathy (EOEE). | 25471517 |
| Type | IDs |
|---|---|
| Synonymous | GLNRS, MSCCA, PRO2195 |
| Gene |
UniProtKB-ID:
SYQ_HUMAN,
B7Z840_HUMAN
UniprotKB:
P47897,
B7Z840
UniParc:
UPI000022C075,
UPI0001915151,
UPI000013661E
EMBL:
X76013,
BC001567,
AK302867,
BC000394,
AK301559,
BC029739,
AC135506
Ensembl:
ENSG00000172053
KO:
hsa:5859
|
| Nucleutide sequences |
EMBL-CDS:
BAG63054.1,
AAH00394.1,
CAA53600.1,
AAH29739.1,
AAH01567.1,
BAH13826.1
Ensembl_TRS:
ENST00000414533,
ENST00000306125
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000390015,
ENSP00000307567
RefSeq:
XP_016862454.2,
NP_001259002.1,
NP_005042.1
|
| Others |
UniRef100:
UniRef100_B7Z840,
UniRef100_P47897
UniRef90:
UniRef90_P47897,
UniRef90_B7Z840
UniRef50:
UniRef50_A0A0U1RQT0,
UniRef50_P47897
UniGene:
Hs.79322
CCDS:
CCDS63633.1,
CCDS2788.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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