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58522 Trim54

58522

Trim54

tripartite motif-containing 54

protein-coding

Mus musculus

基因描述

Type Description
Definition tripartite motif-containing 54

研究结论

Date Results Publications
2016-03-12 10:54:00 findings suggest that MuRF3 helps stabilize cardiac PPARalpha and PPARgamma1 in vivo to support resistance to the development of diabetic cardiomyopathy. MuRF3 also plays an unexpected role in regulating fat storage despite being found only in striated muscle. 26215257
2011-04-09 10:39:00 Knockdown of both MURF2 and MURF3 severely disrupts the formation of ordered Z- and M-bands, likely by perturbed tubulin dynamics 21185285
2010-01-21 00:00:00 muscle RING finger 1 and muscle RING finger 3 as key E3 ubiquitin ligases for the ubiquitin proteasome system-dependent turnover of sarcomeric proteins and reveal a potential basis for myosin storage myopathies 17786241
2010-01-21 00:00:00 MuRF3 has an essential role in maintaining cardiac integrity and function after acute myocardial infarction and turnover of FHL2 and gamma-filamin contributes to this cardioprotective function of MuRF3 17360532

名称对应

Type IDs
Synonymous 4930486E09Rik, 4930566I02Rik, MURF, MURF-3, MuRF3, Rnf30
Gene
UniProtKB-ID: TRI54_MOUSE
UniprotKB: Q9ERP3
UniParc: UPI00000276C7
EMBL: AF294790
Ensembl: ENSMUSG00000062077
KO: mmu:58522
Nucleutide sequences
EMBL-CDS: AAG03076.1
Ensembl_TRS: ENSMUST00000013771
Protein sequencees
Ensembl_PRO: ENSMUSP00000013771
RefSeq: NP_067422.1
Others
UniRef100: UniRef100_Q9ERP3
UniRef90: UniRef90_Q9BYV2
UniRef50: UniRef50_Q9BYV2
UniGene: Mm.143796, Mm.402047
CCDS: CCDS19173.1

全选

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研究热度

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