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58517 RBM25

58517

RBM25

RNA binding motif protein 25

protein-coding

Homo sapiens

基因描述

Type Description
Definition RNA binding motif protein 25

研究结论

Date Results Publications
2020-10-24 13:58:00 Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer. 31586988
2019-05-04 10:05:00 RBM25 binds directly to circAMOTL1L and induces its biogenesis, whereas p53 regulates EMT via direct activation of RBM25 gene. 30531834
2019-02-16 11:23:00 controls the splicing of key genes, including those encoding the apoptotic regulator BCL-X and the MYC inhibitor BIN1 30635567
2017-08-26 12:48:00 Data suggest that RBM25 is required for the viability of multiple human cell lines, suggesting that it could play a key role in pre-mRNA splicing; a region of RBM25 spanning Lys77 binds with high affinity to SRSF2, a crucial protein in exon definition, but only when Lys77 is unmethylated. (RBM25 = RNA binding motif protein 25; SRSF2 = serine- and arginine-rich splicing factor 2) 28655759
2013-03-30 11:27:00 Structure-guided mutagenesis reveals a positively charged nucleic-acid-binding surface in the RBM25 PWI domain 23190262

名称对应

Type IDs
Synonymous NET52, RED120, RNPC7, S164, Snu71, fSAP94
Gene
UniProtKB-ID: RBM25_HUMAN
UniprotKB: P49756
UniParc: UPI00001FD7E9, UPI0001E24F42, UPI0000373D58, UPI0000D47232
EMBL: AF109907, BC136776, AK094697, BC144407, CH471061, AC004858, BC113389, BC111066, AL442663, AK026107, BC113391, BC062440, BC083496, L40392, BC136775
Ensembl: ENSG00000119707
KO: hsa:58517
Nucleutide sequences
EMBL-CDS: BAB15362.1, AAI36776.1, AAI13390.1, BAG52915.1, AAI13392.1, AAH83496.1, AAI36777.1, AAI44408.1, EAW81087.1, AAC97961.1, AAF19255.1, AAI11067.1, AAC41999.1, AAH62440.1
Ensembl_TRS: ENST00000526754, ENST00000527432, ENST00000528081, ENST00000525321, ENST00000261973
Protein sequencees
Ensembl_PRO: ENSP00000261973, ENSP00000434444, ENSP00000431150, ENSP00000436225, ENSP00000436868
RefSeq: XP_024305448.1, NP_067062.1, XP_011535346.1
Others
UniRef100: UniRef100_P49756
UniRef90: UniRef90_P49756
UniRef50: UniRef50_P49756
UniGene: Hs.531106
CCDS: CCDS32113.1

全选

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