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58516 SINHCAF

58516

SINHCAF

SIN3-HDAC complex associated factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition SIN3-HDAC complex associated factor

研究结论

Date Results Publications
2020-08-01 11:11:00 FAM60A act as a carcinogen and suggests that H. pylori-induced upregulation of FAM60A may contribute to the development of gastric cancer. 31727367
2019-04-06 10:53:00 SINHCAF specifically represses HIF-2alpha mRNA and protein expression, via its interaction with the transcription factor SP1 (specificity protein 1) and recruitment of HDAC1 to the HIF-2alpha promoter. 29784889
2018-11-03 11:36:00 FAM60A may act as a key transcriptional factor to regulate genes that are correlated with each cell cycle of tumor cells in esophageal cancer. 28169357
2013-06-29 12:08:00 studies reveal that loss of FAM60A or another component of the Sin3 complex, SDS3, leads to a change in cell morphology and an increase in cell migration 22984288
2012-12-08 10:02:00 Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex. 22865885

名称对应

Type IDs
Synonymous C12orf14, FAM60A, L4, TERA
Gene
UniProtKB-ID: SHCAF_HUMAN
UniprotKB: Q9NP50
UniParc: UPI00000373C6, UPI000006E5CA
EMBL: AY598323, AK026932, AF212220, AC024940, BC071966, BC000024, BC004462, AF087885, AL157432, CH471116
Ensembl: ENSG00000276371, ENSG00000139146
KO: hsa:58516
Nucleutide sequences
EMBL-CDS: BAB15592.1, AAF87322.1, CAB75656.1, AAH00024.1, EAW88566.1, AAH04462.1, EAW88564.1, EAW88561.1, AAH71966.1, EAW88562.1, EAW88567.1, AAT06734.1, AAP97184.1
Gene_ORFName: L4
Ensembl_TRS: ENST00000337682, ENST00000454658, ENST00000631598, ENST00000617411, ENST00000633815, ENST00000633702, ENST00000539409, ENST00000542983
Protein sequencees
Ensembl_PRO: ENSP00000393279, ENSP00000488406, ENSP00000488570, ENSP00000488852, ENSP00000443697, ENSP00000337477, ENSP00000479093, ENSP00000439952
RefSeq: XP_016875247.1, NP_001129284.1, XP_016875251.1, NP_001129283.1, XP_016875248.1, NP_067061.1, XP_016875250.1, XP_016875249.1, XP_011519105.1
Others
UniRef100: UniRef100_Q9NP50
UniRef90: UniRef90_Q9NP50
UniRef50: UniRef50_Q9NP50
UniGene: Hs.505154
CCDS: CCDS8723.1

全选

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