| Type | Description |
|---|---|
| Definition | ovo like zinc finger 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:56:00 | OVOL2 induces mesenchymal-to-epithelial transition in fibroblasts and enhances cell-state reprogramming towards epithelial lineages. | 31019211 |
| 2020-02-22 10:13:00 | These findings suggest that alterations in the ZEB1-OVOL2-GRHL2 axis (caused by posterior polymorphous corneal dystrophy-associated mutations) lead to changes in corneal endothelial cell state and molecular pathways, including the aberrant activation of the Wnt signaling pathway. | 31233731 |
| 2020-02-08 11:25:00 | TRPV1 is a potential therapeutic target in hepatocellular carcinoma and exerts effects on cellular plasticity with modulation of Ovol2, Zeb1 and Sox10. | 31401394 |
| 2019-05-04 10:44:00 | The function of OVOL2 as a tumor suppressor in vivo is highly regulated by PARylation. | 30542118 |
| 2019-04-13 10:09:00 | OVOL2 only exhibits modest effect on epithelial-mesenchymal transition but has a strong impact on both metastasis and tumorigenesis. | 29721073 |
| Type | IDs |
|---|---|
| Synonymous | CHED, CHED1, CHED2, EUROIMAGE566589, PPCD1, ZNF339 |
| Gene |
UniProtKB-ID:
OVOL2_HUMAN
UniprotKB:
Q9BRP0
UniParc:
UPI0000EE704D,
UPI000013C360
EMBL:
AK022284,
AL121585,
BT007295,
BC006148,
AL160411,
AL079276,
CH471133
Ensembl:
ENSG00000125850
KO:
hsa:58495
|
| Nucleutide sequences |
EMBL-CDS:
EAX10258.1,
AAH06148.1,
AAP35959.1,
CAB45151.1,
BAB14002.1,
EAX10259.1
Ensembl_TRS:
ENST00000278780
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000278780
RefSeq:
NP_001290390.1,
NP_067043.2,
NP_001290391.1
|
| Others |
UniRef100:
UniRef100_Q9BRP0
UniRef90:
UniRef90_Q9BRP0
UniRef50:
UniRef50_Q8CIV7
UniGene:
Hs.661013,
Hs.710157
CCDS:
CCDS13132.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员