Type | Description |
---|---|
Definition | junctional adhesion molecule 2 |
Date | Results | Publications |
---|---|---|
2020-07-11 10:07:00 | mutant JAM2 protein resulted in impaired cell-cell adhesion functions and reduced integrity of the neurovascular unit | 31851307 |
2020-05-09 12:33:00 | Along with JAM3 and OCLN, JAM2 is the third tight-junction gene in which bi-allelic variants are associated with brain calcification, suggesting that defective cell-to-cell adhesion and dysfunction of the movement of solutes through the paracellular spaces in the neurovascular unit is a key mechanism in CNS calcification | 32142645 |
2019-10-05 11:04:00 | iR-374b significantly inhibits cell proliferation, migration, and invasion through the blockade of the p38/ERK signaling pathway activation, as well as negatively binding to JAM-2 | 29575013 |
2017-03-18 12:33:00 | this review briefly focuses on what is currently known about the structure, function, and mechanism of JAM-B, with particular emphasis on cancer. [review] | 27121546 |
2016-12-17 12:05:00 | JAM-2 may function as a putative tumour suppressor in the progression and metastasis of colorectal cancer | 26782073 |
Type | IDs |
---|---|
Synonymous | C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM |
Gene |
UniProtKB-ID:
JAM2_HUMAN
UniprotKB:
P57087
UniParc:
UPI000012DAA4,
UPI00017A6E6A,
UPI0000035970
EMBL:
AP000224,
AK294769,
AK312708,
AY077698,
AY016009,
AP000226,
AF255910,
AY358361,
AP000225,
AP000223,
BC017779
Ensembl:
ENSG00000154721
KO:
hsa:58494
|
Nucleutide sequences |
EMBL-CDS:
BAG57900.1,
BAG35586.1,
AAL82538.1,
AAH17779.1,
AAF81223.1,
AAG49022.1,
AAQ88727.1
Gene_ORFName:
UNQ219/PRO245
Ensembl_TRS:
ENST00000400532,
ENST00000312957,
ENST00000480456
|
Protein sequencees |
Ensembl_PRO:
ENSP00000318416,
ENSP00000383376,
ENSP00000420419
RefSeq:
NP_001257337.1,
NP_067042.1,
XP_024307891.1,
XP_024307892.1,
NP_001257336.1
|
Others |
UniRef100:
UniRef100_P57087
UniRef90:
UniRef90_P57087
UniRef50:
UniRef50_P57087
UniGene:
Hs.517227
CCDS:
CCDS58788.1,
CCDS58787.1,
CCDS42911.1
|
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