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5830 PEX5

5830

PEX5

peroxisomal biogenesis factor 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition peroxisomal biogenesis factor 5

研究结论

Date Results Publications
2021-03-28 19:06:00 Mitotic phosphorylation of Pex14p regulates peroxisomal import machinery. 32854114
2019-10-26 11:31:00 The interactions with the docking proteins were independent of the PEX5 ubiquitination status whereas the interactions with the receptor export machinery (REM) components were increased when PEX5 is ubiquitinated 30375424
2019-02-16 10:40:00 These data suggest that PEX5 may be a critical regulator of lysosomal gene expression and autophagy through the mTOR-TFEB-autophagy axis under nutrient deprivation. 29622767
2019-02-09 12:40:00 This study provides evidence suggesting that monoubiquitinated PEX5 interacts directly with both PEX1 and PEX6 through its ubiquitin moiety and that the PEX5 polypeptide chain is globally unfolded during the ATP-dependent extraction event. 29884772
2019-01-12 12:11:00 Data suggest that P7BP2 is localized to peroxisomes by binding to PEX5 via PEX7 in manner dependent on apparent PTS2 (type 2 peroxisomal targeting signal peptide) in N-terminal region of P7BP2; the PTS2 is subsequently cleaved off in peroxisomes. (P7BP2 = PEX7-binding protein-2; PEX5 = peroxisomal biogenesis factor-5; PEX7 = peroxisomal biogenesis factor-7) 30204880

名称对应

Type IDs
Synonymous PBD2A, PBD2B, PTS1-BP, PTS1R, PXR1, RCDP5
Gene
UniProtKB-ID: PEX5_HUMAN, A0A0S2Z4H1_HUMAN, B4E0T2_HUMAN, A0A0S2Z480_HUMAN, A0A0S2Z4F3_HUMAN, B4DR50_HUMAN
UniprotKB: P50542, A0A0S2Z4H1, B4E0T2, A0A0S2Z480, A0A0S2Z4F3, B4DR50
UniParc: UPI00017A839E, UPI00017A7A77, UPI00017A845D, UPI000006E8EC, UPI000016AE82, UPI00001316E7
EMBL: Z48054, BC010621, AK302742, AK316250, KU178294, AC018653, AK299105, CH471116, KU178292, U19721, AK303515, KU178293, X84899, AK292256
Ensembl: ENSG00000288217, ENSG00000139197
KO: hsa:5830
Nucleutide sequences
EMBL-CDS: AAC50103.1, BAH14621.1, AAH10621.1, EAW88674.1, BAG63957.1, BAF84945.1, CAA59324.1, EAW88672.1, CAA88131.1, EAW88671.1, ALQ33751.1, BAG64544.1, ALQ33750.1, ALQ33752.1, BAG61162.1
Ensembl_TRS: ENST00000266564, ENST00000420616, ENST00000672242, ENST00000672776, ENST00000672541, ENST00000455147, ENST00000434354, ENST00000672694, ENST00000671993, ENST00000266563, ENST00000412720
Protein sequencees
Ensembl_PRO: ENSP00000266563, ENSP00000500696, ENSP00000400647, ENSP00000500509, ENSP00000410159, ENSP00000266564, ENSP00000500230, ENSP00000407401, ENSP00000500043, ENSP00000499823, ENSP00000391601
RefSeq: NP_001124496.1, XP_016875234.1, NP_001338063.1, NP_001124498.1, NP_001338055.1, NP_001338062.1, NP_001361575.1, NP_001124497.1, NP_001361578.1, NP_000310.2, NP_001338057.1, NP_001338060.1, NP_001338064.2, NP_001338053.1, XP_011519095.1, NP_001124495.1, NP_001287718.2, NP_001361577.1, XP_016875237.1, NP_001338069.1, NP_001338066.2, NP_001361574.1, NP_001361576.1, NP_001338056.1, XP_011519104.1, XP_011519097.1, NP_001338067.1, NP_001338068.1, NP_001338059.1, NP_001338065.1, NP_001338061.1, XP_016875238.1
Others
UniRef100: UniRef100_A0A2J8TBX5, UniRef100_B4DR50, UniRef100_B4E0T2, UniRef100_B4DWW0, UniRef100_P50542
UniRef90: UniRef90_O09012-2, UniRef90_P50542
UniRef50: UniRef50_P50542
UniGene: Hs.567327
CCDS: CCDS44822.1, CCDS8576.1, CCDS73433.1, CCDS44823.1, CCDS44824.1

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