Type | Description |
---|---|
Definition | paxillin |
Date | Results | Publications |
---|---|---|
2020-04-18 12:18:00 | Microarray, gain, or loss of function and luciferase report assays revealed the direct regulatory effect of ETV4 on the expression of focal adhesion gene PXN and matrix metalloproteinase 1 (MMP1), and PXN and/or MMP1 inhibition partially abolished cell proliferation and migration induced by ETV4. | 31670855 |
2019-02-02 10:44:00 | Glucosamine affects signaling pathway activation of NK-92 immune cells, changing the phosphorylation of FOXO1, paxillin, and the ERK map kinase pathway | 30016365 |
2018-11-03 12:05:00 | Data suggest that FGFR3 with mutation found in patients with SADDAN (but not FGFR3 with mutation found in patients with TDII) affects cytoskeleton organization in chondrocytes by inducing tyrosine hyperphosphorylation of paxillin. (FGFR3 = fibroblast growth factor receptor 3; SADDAN = Severe Achondroplasia with Developmental Delay and Acanthosis Nigricans; TDII = Thanatophoric Dysplasia type II) | 29242050 |
2018-09-15 12:04:00 | overexpression of Paxillin significantly decreased tumor volume of colorectal cancer; miR-24 was overexpressed in natural killer cells and inhibited paxillin expression. | 29494963 |
2018-09-01 10:52:00 | XIST positively regulated PXN levels by sponging miR-137 in vitro and in vivo. Collectively, our study provided the evidence for the cross-talk between XIST, miR-137, and PXN, shedding light on the therapy for non-small cell lung cancer . | 29337100 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
PAXI_HUMAN,
A0A140VJQ8_HUMAN
UniprotKB:
P49023,
A0A140VJQ8
UniParc:
UPI00001FBC71,
UPI0001711D29,
UPI000013C8CD,
UPI0000E00CD4
EMBL:
D86863,
U14588,
CH471054,
U87944,
BC136794,
AC004263,
AK314204,
D86862,
U87943,
HM005447,
BC144410,
BX648777,
U87942,
U87945,
U87941,
BC136787,
U87946
Ensembl:
ENSG00000089159
KO:
hsa:5829
|
Nucleutide sequences |
EMBL-CDS:
AAC50104.1,
AAD00648.1,
AAI44411.1,
CAI46024.1,
AAC05175.1,
BAG36880.1,
AAI36795.1,
AAI36788.1,
BAA18998.1,
BAA18997.1,
AEE61045.1,
EAW98179.1
Gene_ORFName:
hCG_27772
Ensembl_TRS:
ENST00000424649,
ENST00000267257,
ENST00000458477,
ENST00000228307
|
Protein sequencees |
Ensembl_PRO:
ENSP00000228307,
ENSP00000395536,
ENSP00000267257,
ENSP00000391283
RefSeq:
XP_016875229.1,
XP_006719599.1,
XP_024304877.1,
NP_001372913.1,
XP_006719597.1,
NP_001372914.1,
XP_016875215.1,
XP_016875223.1,
XP_011536924.1,
XP_016875222.1,
XP_016875219.1,
XP_005253974.1,
NP_001372911.1,
XP_024304875.1,
XP_016875232.1,
XP_016875227.1,
NP_001372919.1,
XP_016875231.1,
XP_016875228.1,
NP_001372910.1,
NP_001372916.1,
NP_001372915.1,
XP_016875225.1,
NP_001230685.1,
XP_016875224.1,
NP_001074324.1,
XP_016875221.1,
XP_024304878.1,
NP_002850.2,
XP_016875226.1,
NP_001372918.1,
NP_001372912.1,
NP_079433.3,
XP_006719598.1,
XP_011536925.1,
XP_006719595.1,
XP_016875218.1,
NP_001372917.1,
XP_024304876.1
|
Others |
UniRef100:
UniRef100_P49023
UniRef90:
UniRef90_P49023
UniRef50:
UniRef50_P49023
UniGene:
Hs.446336
CCDS:
CCDS44998.1,
CCDS44996.1,
CCDS44997.1,
CCDS58281.1
|
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Refseq |
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